DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and wdr47

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:XP_031756900.1 Gene:wdr47 / 100127667 XenbaseID:XB-GENE-5787016 Length:919 Species:Xenopus tropicalis


Alignment Length:462 Identity:103/462 - (22%)
Similarity:172/462 - (37%) Gaps:140/462 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 RSLKRTHDLFVSNQGNLPEIDERLE---KLRR-----SIKAKDGYGLVLDKVAKIGEARKASGAQ 73
            ||:|:..:|   |.|..| ::|.::   ||..     ||.|.:|:       :.:|.|....|.|
 Frog   482 RSIKKLGEL---NVGMEP-LEEGIQPKNKLHNGPRESSIMAPNGH-------SPLGTAVLQRGNQ 535

  Fly    74 TPGDKTLAITDGSATDAASGAGSLVKY-----------------------NAGARPAEKT----- 110
            .|..:::    .::|....||.|.:.:                       ..|||...:|     
 Frog   536 QPDGQSI----NTSTPRKRGATSYIPFPEESPVFGSANSAREQVQLEDSSGTGARKCSETDKKQQ 596

  Fly   111 -APLVTGTHTSLVRASLANSNADMSANGAIASHLQL-------------IPKKAPSIPKPKWHAP 161
             ..|.:...|..|||...:.:..:.|.|:.:..|::             .|.:.|...|...|  
 Frog   597 FVCLTSLEDTQAVRAVAFHPSGSLYAVGSNSKTLRVCAYPDVIDTSNSNCPTQPPVRFKRNKH-- 659

  Fly   162 WKLSRVISGHLGWVRCIAVEPGNEWFATGAGDRVIK------------------------IWDLA 202
                     |.|.:.|:|..|..:..|||:.|:.:|                        |.|||
 Frog   660 ---------HKGSIYCVAWSPCGQLLATGSNDKYVKVLPFSAETCNATGPDLEFSMHDGTIRDLA 715

  Fly   203 -------SGKLKLS---------------------LTGHVSTVRGVAVSTKHPYLFSCG-EDRQV 238
                   .|.:.:|                     |:||...:  :|:.|...::.:.| :|:.|
 Frog   716 FMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHI--LALYTWSGWMIASGSQDKTV 778

  Fly   239 KCWDLEYNKVIR----HYHGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTN 299
            :.|||.....:|    .:||..|||.|:|:.|:..:|||...||:..::|:|....|.:...|::
 Frog   779 RFWDLRVPSCVRVIGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSS 843

  Fly   300 TVASVVAQATNPQIITGSHDSTVRLWDLAAGKS----VCTLTNHKKSVRSIVLHPSLYMFASASP 360
            .|.||........::|||:|..|::.||....:    :..:..||..|.....|.....|.|:|.
 Frog   844 DVRSVRFSPGAHYLLTGSYDMKVKVTDLQGDLTKPLPIIEVGEHKDKVIQCRWHTQDLSFLSSSA 908

  Fly   361 D-NIKQW 366
            | .:..|
 Frog   909 DRTVSLW 915

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 64/268 (24%)
WD40 164..458 CDD:238121 64/265 (24%)
WD40 repeat 177..212 CDD:293791 15/86 (17%)
WD40 repeat 218..254 CDD:293791 9/40 (23%)
WD40 repeat 259..295 CDD:293791 12/35 (34%)
WD40 repeat 302..337 CDD:293791 9/38 (24%)
WD40 repeat 343..378 CDD:293791 7/25 (28%)
WD40 repeat 386..426 CDD:293791
WD40 repeat 433..457 CDD:293791
wdr47XP_031756900.1 LisH_TPL 13..40 CDD:375350
CTLH 47..102 CDD:128914
Myosin_tail_1 <422..>500 CDD:396244 7/21 (33%)
WD40 606..915 CDD:238121 74/321 (23%)
WD40 repeat 611..659 CDD:293791 7/47 (15%)
WD40 repeat 665..706 CDD:293791 8/40 (20%)
WD40 repeat 711..752 CDD:293791 6/40 (15%)
WD40 repeat 762..795 CDD:293791 8/32 (25%)
WD40 repeat 803..837 CDD:293791 12/33 (36%)
WD40 repeat 845..885 CDD:293791 10/39 (26%)
WD40 repeat 891..915 CDD:293791 6/23 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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