DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tango4 and cop1

DIOPT Version :9

Sequence 1:NP_572778.1 Gene:Tango4 / 32168 FlyBaseID:FBgn0030365 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_001083011.1 Gene:cop1 / 100037391 ZFINID:ZDB-GENE-070410-134 Length:694 Species:Danio rerio


Alignment Length:325 Identity:67/325 - (20%)
Similarity:119/325 - (36%) Gaps:81/325 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 DLASGKLKLSLTGHVSTVRGVAVSTKHPYLFSCGEDRQVKCWDLEYNKVIR-----HY------- 252
            ||.:|.         |.|..:.......|....|..:::|.:  ||..||:     ||       
Zfish   379 DLYNGS---------SIVSSIEFDRDCDYFAIAGVTKKIKVF--EYGTVIQDAVDIHYPVNEMTC 432

  Fly   253 HGHLSAVYSLALHPTIDVLATSGRDSTARIWDMRTKANVHTLTGHTNTVASVVAQATNPQII-TG 316
            :..:|.:...:.|.  ::||:|..:.|..:||..|.........|.....||.....:|::: :|
Zfish   433 NSKISCISWSSYHK--NLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASG 495

  Fly   317 SHDSTVRLW---------DLAAGKSVC------------------------TLTNHKKSVRSIVL 348
            |.|:.|:||         .:.|..:||                        .|.|.|:.:.....
Zfish   496 SDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPTSRYHLAFGCADHCVHYYDLRNAKQPIMVFKG 560

  Fly   349 HPSLYMFA---------SASPDN-IKQWRCPEGKFVQNISGHTSIVNCMAANSEGVLVS-GGDNG 402
            |.....:|         |||.|: :|.|...:...:::..||.:..|.:...|.|..|: |.:|.
Zfish   561 HRKAVSYAKFVNGGEIVSASTDSQLKLWNVNKPHCLRSFKGHINEKNFVGLASNGDYVACGSENN 625

  Fly   403 TMFFW-----DWRTGYNFQRFQAPVQPGSMDSEAGIF--AMCF----DQSGSRLITAEADKTIKV 456
            :::.:     .....:.|...::.:.....:.:...|  |:|:    |...:.||.|.:..||||
Zfish   626 SLYLYCKGLSKTLLTFKFDTVKSVLDKDKKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKV 690

  Fly   457  456
            Zfish   691  690

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tango4NP_572778.1 WD40 <161..458 CDD:225201 67/325 (21%)
WD40 164..458 CDD:238121 67/325 (21%)
WD40 repeat 177..212 CDD:293791 3/11 (27%)
WD40 repeat 218..254 CDD:293791 9/47 (19%)
WD40 repeat 259..295 CDD:293791 8/35 (23%)
WD40 repeat 302..337 CDD:293791 12/68 (18%)
WD40 repeat 343..378 CDD:293791 8/44 (18%)
WD40 repeat 386..426 CDD:293791 6/45 (13%)
WD40 repeat 433..457 CDD:293791 11/30 (37%)
cop1NP_001083011.1 zf-C3HC4 98..135 CDD:278524
NAM-associated <200..260 CDD:291001
WD40 384..690 CDD:238121 62/318 (19%)
WD40 repeat 387..418 CDD:293791 7/32 (22%)
WD40 repeat 436..473 CDD:293791 9/38 (24%)
WD40 repeat 480..516 CDD:293791 9/35 (26%)
WD40 repeat 521..559 CDD:293791 5/37 (14%)
WD40 repeat 565..600 CDD:293791 7/34 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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