DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment regucalcin and yellow-d2

DIOPT Version :9

Sequence 1:	NP_727588.2	Gene:	regucalcin / 32165	FlyBaseID:	FBgn0030362	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_611788.1	Gene:	yellow-d2 / 37704	FlyBaseID:	FBgn0034856	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	41/196 - (20%)
Similarity:	66/196 - (33%)	Gaps:	56/196 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GLTMSYKVEP-------LPDSYAGLGEGPHWDVARQSLYYVDLEAGSLLRYDYAQNKVYKTKIEG 71
            |||..|:.:.       :.||    ||..........||.:|||:|.:........::||
  Fly   120 GLTSVYRTQIDECGRMWILDS----GEIDFIQHCPPQLYAIDLESGKVAHQYKMPKRLYK----- 175

  Fly    72 ETLAGFVLP-VEGRPQEFAVGCGRRVVIVNWDGVSPSAKVVRTLFEVQPLMEKNRLNDAKVDPRG 135
            |.::.||.| ||..|....||.......:. ||:        .:::| ...:..|:.:....|..
  Fly   176 EGVSRFVTPTVELDPHNCDVGFVYMADSIG-DGI--------VVYDV-AAQQSWRIENKFTYPHP 230

  Fly   136 RFFGGTMRYIGDEFE---------------------FRHGELYRWEAGGQVSVIKGDVGISNGLA 179
            .|  ||....|:.|:                     :.|.....|:....:.|      ::||..
  Fly   231 DF--GTFTIAGESFQLWDGTVSTTLTPHGLGGRRMMYFHSLSSEWQMAIPLDV------VNNGSN 287

  Fly   180 W 180
            |
  Fly   288 W 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
regucalcin	NP_727588.2	SGL	31..290	CDD:285626	35/172 (20%)
		NHL	<229..302	CDD:302697
		NHL repeat	229..259	CDD:271320
yellow-d2	NP_611788.1	MRJP	122..411	CDD:281074	39/194 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3386
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900