Protein Alignment regucalcin and Rgn

DIOPT Version :9

• Sequence 1: NP_727588.2
• Gene: regucalcin / 32165
• FlyBaseID: FBgn0030362
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_113734.1
• Gene: Rgn / 25106
• RGDID: 3560
• Length: 299
• Species: Rattus norvegicus
• Alignment Length: 314
• Identity: 107/314 - (34%)
• Similarity: 152/314 - (48%)
• Gaps: 45/314 - (14%)

  Fly    18 SYKVE-PLPDSYAGLGEGPHWDVARQSLYYVDLEAGSLLRYDYAQNKVYKTKIEGETLA------ 75
            |.|:| .|.::|. .||.|.|:.|.:.|.:||:.:.::.|:|...|:|.:..::....:
  Rat     3 SIKIECVLRENYR-CGESPVWEEASKCLLFVDIPSKTVCRWDSISNRVQRVGVDAPVSSVALRQS 66

  Fly    76 -GFVLPVEGRPQEFAVGCGRRVVIVNWDGVSPSAKVVRTLFEVQPLMEKNRLNDAKVDPRGRFFG 139
             |:|..:           |.:...:||:..|     |..|..|....:.||.||.||||.||:|.
  Rat    67 GGYVATI-----------GTKFCALNWEDQS-----VFILAMVDEDKKNNRFNDGKVDPAGRYFA 115

  Fly   140 GTMRYIGDE-----FEFRHGELYRWEAGGQVSVIKGDVGISNGLAWDEKAKKFYYIDTTDYEVKS 199
            |||   .:|     .|...|.||.......|......|.|||||.|....|.|||||:..|.|.:
  Rat   116 GTM---AEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDA 177

  Fly   200 YDYDFETGVASNPKVIFNLRKNSPKDHLLPDGLTIDTEGNLYVATFNGATIYKVNPNTGKILLEI 264
            :|||..||..||.:.::.:.    ||..:|||:.||.||.|:||.:||..:.:::|.|||.|..:
  Rat   178 FDYDLPTGQISNRRTVYKME----KDEQIPDGMCIDVEGKLWVACYNGGRVIRLDPETGKRLQTV 238

  Fly   265 KFPTKQITSAAFGGPNLDILYVTTA-------AKFDQPAPAGTTYKVTGLNATG 311
            |.|..:.||..|||.:...:|||.|       ....|| .||..:|:|||...|
  Rat   239 KLPVDKTTSCCFGGKDYSEMYVTCARDGMSAEGLLRQP-DAGNIFKITGLGVKG 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
regucalcin	NP_727588.2	SGL	31..290	CDD:285626	93/277 (34%)
		NHL	<229..302	CDD:302697	32/79 (41%)
		NHL repeat	229..259	CDD:271320	14/29 (48%)
Rgn	NP_113734.1	SGL	16..264	CDD:285626	92/270 (34%)
		NHL	166..>237	CDD:302697	32/74 (43%)
		WD40 repeat	203..239	CDD:293791	17/35 (49%)
		NHL repeat	203..237	CDD:271320	17/33 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334779
Domainoid	1	1.000	155	1.000	Domainoid score	I4141
eggNOG	1	0.900	-	-		E1_COG3386
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3437
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4078
OMA	1	1.010	-	-		QHG61138
OrthoDB	1	1.010	-	-		D1343872at2759
OrthoFinder	1	1.000	-	-		FOG0003598
OrthoInspector	1	1.000	-	-		otm45260
orthoMCL	1	0.900	-	-		OOG6_101744
Panther	1	1.100	-	-	LDO	PTHR10907
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2470
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770