DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1492 and si:dkey-222h21.12

DIOPT Version :9

Sequence 1:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_021333865.1	Gene:	si:dkey-222h21.12 / 795959	ZFINID:	ZDB-GENE-090312-33	Length:	605	Species:	Danio rerio

Alignment Length:	578	Identity:	182/578 - (31%)
Similarity:	291/578 - (50%)	Gaps:	76/578 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 RAAICSDSDVCSQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSI 123
            :||:.:|:::||::.:.:|...|||||.|:|||:|..:|..||||||||.|..:|.|.......|
Zfish    39 KAAVAADAEICSKIGRDILGRNGSAVDAAIAALLCVSVINPQSMGIGGGSVFTIYNAINGTVEII 103

  Fly   124 LAREMAPLALRADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELCRR 188
            .|||.||::..|:.|.:...:::   .|..||||.||.||.:||.|:|:|.||||..|:::|...
Zfish   104 NARETAPMSATANMFDNNTQKEN---PGLLIAVPGELRGYKMAHDRYGKLPWKDLFEPSIKLASE 165

  Fly   189 GYRLYKHQYDALILNQDMIRADSGLRRMFIDPDT--------GRFWPLGHLIRPAAQLCNTYDRL 245
            |:.:.|....|:.:.:..||.:..||.:|.|.|.        .||          .:|..||..:
Zfish   166 GFNISKGLAYAINMEERKIRKNIALREVFCDSDNKPLKESNFTRF----------PKLAKTYRTI 220

  Fly   246 ANEGPLSFYRGSIADDLLADLKDAGSAITKEDLNQAHAKLSS-AIVMPLDEYDLHLTPPPGSGHV 309
            |.|||.:||.||:...:|.::..||..||:|||.:....|.. |:...:.:|.......|..|.|
Zfish   221 AEEGPDAFYDGSLTQSILDEITVAGGNITREDLKRYKPDLQKYALNFTVGKYIFFAPTAPFGGPV 285

  Fly   310 LGFIMNIL---------KEFRAEFSRAGTMSPRQI----------HLMVEAMKFGFVKRWQLDES 355
            |..||.||         |.....:.....:|.:.:          |.::||.:|...::.:|.:.
Zfish   286 LALIMKILLGNGTAGSSKSHLLHYYSGFNLSNKSVSTPENMTLTYHRIIEAFRFANAQKAKLADP 350

  Fly   356 ASE----ELLSNLTSHELAKSVARQINHTHTFNRPEFYGAS---PGIQI-RDEHGTAHTSVL-HG 411
            ..|    |.:..:||...|.::..:|       :.:....|   .||:| .|:|||:|.||: ..
Zfish   351 LHEKNVTEFVKYMTSDSFADNIRNKI-------KDDIKQTSYDEQGIKIVPDDHGTSHLSVIAKD 408

  Fly   412 NDAVSVTSSINFYFGSGRTGRRTGVIFNNAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMC 476
            ..||:||||||.:||||......|:|||:.|||::..::||        |.|.:.|..||:||||
Zfish   409 GSAVAVTSSINNFFGSGVMSCLRGIIFNDQMSDYTSPEMKN--------GPNAIKPGKRPLSSMC 465

  Fly   477 PVIVTERATGNVRLVVGAAGGTKIISALSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYG 541
            |.|:.::.:..||:|.|.||||.|.::::.:::..|:.:.:::.|:...|:  |:.|||...|.|
Zfish   466 PTIILDKDSRKVRMVAGGAGGTNITTSVAQVILDHLYFDYNLQKAVAEPRV--QVPPNVTNVEEG 528

  Fly   542 LRQSYVDSLAERGHRCERY---------ENRGSVICGIAQANDTIWVNSDFRKPGGVS 590
            ...:.:..|:.:.|...:|         |..||.:|.::...|.::.........|:|
Zfish   529 FDSTVMGWLSRKYHNISQYTSLTMVQVVEKEGSQVCAVSDTRDAVYYRPSTASVKGLS 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1492	NP_001303553.1	G_glu_transpept	76..587	CDD:279371	175/556 (31%)
si:dkey-222h21.12	XP_021333865.1	G_glu_transpept	55..570	CDD:307247	174/544 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.890