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Protein Alignment CG1492 and GGT2

DIOPT Version :9

Sequence 1:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001338233.1	Gene:	GGT2 / 728441	HGNCID:	4251	Length:	574	Species:	Homo sapiens

Alignment Length:	613	Identity:	199/613 - (32%)
Similarity:	316/613 - (51%)	Gaps:	71/613 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IGLNSLISVVIVILVAVYIYRYPDGNAGKKKASRRPPNPEDPLPPSNSPLHRFSRAAICSDSDVC 69
            :||.:::.|::::.:.:::          ..||:.|.|            |.::|||:.:|:..|
Human     8 LGLLAVVLVLVIVGLCLWL----------PSASKEPDN------------HVYTRAAMAADAKQC 50

  Fly    70 SQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSILAREMAPLALR 134
            .::.:..|.:||||||.|:|||:|.||:...|||||.|:.:.:|.:..::|..|.|||:||....
Human    51 LEIGRDTLRDGGSAVDAAIAALLCVGLMNAHSMGIGVGLFLTIYNSTTHESEVINAREVAPRLAF 115

  Fly   135 ADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELCRRGYRLYKHQYDA 199
            |..|:|....|   :.|.|:|||.|:.||.:||||.|||.|..|..|:::|.|:|:.:.|.....
Human   116 ASMFNSSEQSQ---KGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAV 177

  Fly   200 LILNQDMIRADSGL------------RRMFIDPDTGRFWPLGHLIRPAAQLCNTYDRLANEGPLS 252
            |...:.:|.....|            |::..:.:        .|..|  :|.:||:.||.||..:
Human   178 LENKRTVIEQQPVLCPLCPGEVFCRDRKVLREGE--------RLTLP--RLADTYEMLAIEGAQA 232

  Fly   253 FYRGSIADDLLADLKDAGSAITKEDLNQAHAKL-SSAIVMPLDEYDLHLTPPPGSGHVLGFIMNI 316
            ||.||:...::.|::.||..:|.||||...|:| ...:.:.|.:..|::.....||.||..|:||
Human   233 FYNGSLMAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSARLSGPVLALILNI 297

  Fly   317 LKEFRAEFSRAGTMSPRQ----IHLMVEAMKFGFVKRWQLDESA---SEELLSNLTSHELAKSVA 374
            ||.:  .|||....:|.|    .|.:|||.:|.:.||..|.:..   ..|::.|:||...|..:.
Human   298 LKGY--NFSRESVETPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLR 360

  Fly   375 RQIN----HTHTFNRPEFYGASPGIQIRDEHGTAHTSVL-HGNDAVSVTSSINFYFGSGRTGRRT 434
            .||:    |..::.:||||  :|     |:.||||.||: ....|||.||:||.||||......:
Human   361 SQISDHTTHPISYYKPEFY--TP-----DDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVS 418

  Fly   435 GVIFNNAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIVTERATGNVRLVVGAAGGTK 499
            |::|||..:..::....|.|..|..| .|.:.|..:|:.|||..|:..: .|.||:||||||||:
Human   419 GILFNNEWTTSALPAFTNEFGAPPSP-ANFIQPGKQPLLSMCLTIMVGQ-DGQVRMVVGAAGGTQ 481

  Fly   500 IISALSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYGLRQSYVDSLAERGHRCERYENRG 564
            |.:..:..::..||....:|.|::..|:|:::||||...|..:.|:...:|..|.|..:......
Human   482 ITTDTALAIIYNLWFGYDVKRAVEEPRLHNKLLPNVTTVERNIDQAVTAALETRHHHTQIASTFI 546

  Fly   565 SVICGIAQANDTIWVNSDFRKPGGVSGF 592
            :|:..|.:........||.||.|..:|:
Human   547 AVVQAIVRTAGGWAAASDSRKGGEPAGY 574

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.