DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1492 and CG17636

DIOPT Version :9

Sequence 1:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001245442.1	Gene:	CG17636 / 5740847	FlyBaseID:	FBgn0025837	Length:	585	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	165/506 - (32%)
Similarity:	262/506 - (51%)	Gaps:	31/506 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 AICSDSDVCSQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSILA 125
            |:.|:...|:::...:|:.||||.|.|:|.::|.|::...|:|:|||.|..:|..:...|..::|
  Fly    55 AVASNGVGCAEVGGSILDIGGSAADAAIATMLCEGVMLPHSLGVGGGFVATIYSRETEFSEVLIA 119

  Fly   126 REMAPLALRADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELCRRGY 190
            ||.||.|...|.|....     .....|.|||||:.||:..|.::|||.||.|..||::|||||.
  Fly   120 RETAPAAATQDMFVKTE-----ITGALSCAVPAEIYGYSELHDKYGRLPWKTLFQPTIDLCRRGI 179

  Fly   191 RLYKHQYDALILNQDMIRADSGLRRMFIDPDTGRFWPLGHLIRPAAQLCNTYDRLANEGPLSFYR 255
            .:.::....|...::.||.:..:..:||:|.|...:..|.::. ...|..|.:.:|:||..:.|.
  Fly   180 LVSRYLSGVLQREEERIRNEPSMAEIFINPKTDEVYKQGEVMY-RHTLAETLEIIADEGAKAIYG 243

  Fly   256 GS-IADDLLADLKDAGSAITKEDLNQAHAKLSSAIVMPLDE-----YDLHLTPPPGSGHVLGFIM 314
            |. :...|:.|::..|..:|:|||...:.:..    |||..     |.|..:..|.||.||.|::
  Fly   244 GGRVGRKLVEDIQAMGGIVTEEDLQSYNVRWE----MPLHSHFSGGYKLITSTLPTSGAVLTFML 304

  Fly   315 NILKEFRAEFSRAGTMSPRQIHLMVEAMKFGFVKRWQLD----ESASEELLSNLTSHELAKSVAR 375
            |:::....      :.:.:....::|..|..:..|..|.    |...:|:..||.....|..:.:
  Fly   305 NVMEPLYT------SNTDKYWQRLIETFKHAYGHRTNLGDIHYEPDVQEMYENLIDPAFAAEIRK 363

  Fly   376 QINHTHTFNRPEFYGASPGIQIRDEHGTAHTSVLHGN-DAVSVTSSINFYFGSGRTGRRTGVIFN 439
            .|....||....:|||:  ....::|||||.|||..| ||:||||:||.:.|:....|:||.|.|
  Fly   364 LILDDRTFEDMSYYGAN--FANEEDHGTAHISVLAPNGDAISVTSTINSHLGAKVRSRQTGFILN 426

  Fly   440 NAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIVTERATGNVRLVVGAAGGTKIISAL 504
            :.|.|||.....|.:.:|..| .|.:.|..|||||.||.||.: ..|||:|:||.|||:||.:::
  Fly   427 DEMDDFSTPGKINAYGIPASP-ANFIKPGKRPMSSTCPSIVLD-THGNVKLIVGGAGGSKITTSV 489

  Fly   505 SPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYGLRQSYVDSLAERGH 555
            :..::|.......|:.|:::.|:|||:.|..:..|..:.:..|..|:..||
  Fly   490 AQTILRYFVLHEPIEKAVNSGRLHHQLAPMHIDMEPNVPRHTVAYLSAIGH 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1492	NP_001303553.1	G_glu_transpept	76..587	CDD:279371	162/491 (33%)
CG17636	NP_001245442.1	G_glu_transpept	69..574	CDD:279371	162/492 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447727
Domainoid	1	1.000	227	1.000	Domainoid score	I423
eggNOG	1	0.900	-	-		E1_COG0405
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	227	1.000	Inparanoid score	I741
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		otm51323
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
	10	9.900