DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1492 and ggt1l2.2

DIOPT Version :9

Sequence 1:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	XP_009294029.1	Gene:	ggt1l2.2 / 566746	ZFINID:	ZDB-GENE-090312-37	Length:	566	Species:	Danio rerio

Alignment Length:	609	Identity:	191/609 - (31%)
Similarity:	309/609 - (50%)	Gaps:	83/609 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SLISVVIVILVAVYIYRYPDGNAGKKKASRRPPNPEDPLPPSNSPLHRFSRAAICSDSDVCSQLA 73
            ||:.:|||||:.|.|..                        ||:   .:..||:.:|:..||::.
Zfish    16 SLVIIVIVILIVVRIVL------------------------SNT---CYDNAAVAADARKCSEIG 53

  Fly    74 KKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSILAREMAPLALRADNF 138
            :.:|:..|||||.|:|||:|..|:..||||||||:|..:|.|...|..:|.:||.||::...:.|
Zfish    54 RDILQRNGSAVDAAIAALLCVSLVNAQSMGIGGGLVFTIYNAPSGKVETINSRETAPMSASENMF 118

  Fly   139 SSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELCRRGYRLYKHQYDALILN 203
            .:   ..:..:.|..||||.||.|||:||:|.|:|.||:|..|:::|...|:::.|...:|:...
Zfish   119 GT---NPEKAKPGLFIAVPGELRGYALAHKRHGKLPWKELFQPSIKLASEGFKIGKALANAINET 180

  Fly   204 QDMIRADSGLRRMFIDP--------DTGRFWPLGHLIRPAAQLCNTYDRLANEGPLSFYRGSIAD 260
            :..|:.::.|..:|.|.        ||.||          .:|..||.:::.|||.:||.||:..
Zfish   181 RATIQRNATLCEVFCDSNNIVLKENDTIRF----------PKLAETYRKISEEGPDAFYNGSLTQ 235

  Fly   261 DLLADLKDAGSAITKEDLNQAHAKLSS-AIVMPLDEYDLHLTPPPGSGHVLGFIMNILKEFRAEF 324
            .::.|:|.||..||:|||......|:. |:...:.:|..|....|..|.||..|:.::|.:...:
Zfish   236 SIVDDIKAAGGIITREDLKAYGPVLTEHALNFTVGKYIFHAPGAPFGGPVLALILKVMKGYNISW 300

  Fly   325 SRAGTMSPRQI--HLMVEAMKFGFVKRWQLDESASE---ELLSNLTSHELAKSVARQIN---HTH 381
            ....|...:.:  |.::||.:|..|::.:|.:...|   |.:.|:.|...|..:..:|.   ...
Zfish   301 KSMATTGNKTLTYHRLIEAFRFADVQKSKLGDPLFENITEHVKNMVSDSFADHIRSKIKDDLKQT 365

  Fly   382 TFNRPEFYGASPGIQIRDEHGTAHTSVL-HGNDAVSVTSSINFYFGSGRTGRRTGVIFNNAMSDF 445
            :::..|.....|     ::|||:|.||| ....||:||||||.|||||...|.||:|||:.|.||
Zfish   366 SYDEQEDINTVP-----EDHGTSHVSVLAKDGSAVAVTSSINNYFGSGVMSRSTGIIFNDQMWDF 425

  Fly   446 SIEQL-----KNYFDLPFVPGTNGVAPAARPMSSMCPVIVTER--ATGNVRLVVGAAGGTKIISA 503
            ...:|     ||          |.:.|..||:|||||.|:.|:  ....||:|||.||||.|.::
Zfish   426 IEPELMSGPNKN----------NKIKPGKRPLSSMCPTIIFEKDDRKNKVRMVVGGAGGTNITTS 480

  Fly   504 LSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYGLRQSYVDSLAERGHRCERYENRGSVIC 568
            ::.:::..|:....::.:::.||:  |:..||...|....::.::.|.::.|.. .::...||:.
Zfish   481 VAQVILNHLFFGFDLQKSVNTSRV--QITLNVTNVEKDFDKAVIEGLKQKNHHI-LHDTALSVVQ 542

  Fly   569 GIAQANDTIWVNSDFRKPGGVSGF 592
            .|.:....:...||.|..|..:|:
Zfish   543 AIGRKGKKVCAQSDTRNDGHAAGY 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1492	NP_001303553.1	G_glu_transpept	76..587	CDD:279371	173/535 (32%)
ggt1l2.2	XP_009294029.1	G_glu_transpept	55..561	CDD:279371	173/536 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D176986at33208
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.890