Protein Alignment CG1492 and GGT1

DIOPT Version :10

• Sequence 1: NP_572774.1
• Gene: CG1492 / 32164
• FlyBaseID: FBgn0030361
• Length: 592
• Species: Drosophila melanogaster
• Sequence 2: NP_038265.2
• Gene: GGT1 / 2678
• HGNCID: 4250
• Length: 569
• Species: Homo sapiens
• Alignment Length: 606
• Identity: 213/606 - (35%)
• Similarity: 325/606 - (53%)
• Gaps: 62/606 - (10%)

  Fly     5 IGLNSLISVVIVILVAVYIYRYPDGNAGKKKASRRPPNPEDPLPPSNSPLHRFSRAAICSDSDVC 69
            :||.:::.|::::.:.:::          ..||:.|.|            |.::|||:.:|:..|
Human     8 LGLLAVVLVLVIVGLCLWL----------PSASKEPDN------------HVYTRAAVAADAKQC 50

  Fly    70 SQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSYSILAREMAPLALR 134
            |::.:..|.:||||||.|:|||:|.||:...|||||||:.:.:|.:...|:..|.|||:||....
Human    51 SKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAF 115

  Fly   135 ADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELCRRGYRLYKHQYDA 199
            |..|:|....|   :.|.|:|||.|:.||.:||||.|||.|..|..|:::|.|:|:.:.|....|
Human   116 ATMFNSSEQSQ---KGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAA 177

  Fly   200 L-----ILNQDMIRADSGLRRMFIDPDTGRFWPLGHLIRPAAQLCNTYDRLANEGPLSFYRGSIA 259
            |     ::.|..:..:...|...:..:..|      |..|  ||.:||:.||.||..:||.||:.
Human   178 LENKRTVIEQQPVLCEVFCRDRKVLREGER------LTLP--QLADTYETLAIEGAQAFYNGSLT 234

  Fly   260 DDLLADLKDAGSAITKEDLNQAHAKL-SSAIVMPLDEYDLHLTPPPGSGHVLGFIMNILKEFRAE 323
            ..::.|::.||..:|.||||...|:| ...:.:.|.:..|::...|.||.||..|:||||.:  .
Human   235 AQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGY--N 297

  Fly   324 FSRAGTMSPRQ----IHLMVEAMKFGFVKRWQLDESA---SEELLSNLTSHELAKSVARQIN--- 378
            |||....||.|    .|.:|||.:|.:.||..|.:..   ..|::.|:||...|..:..||:
Human   298 FSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDT 362

  Fly   379 -HTHTFNRPEFYGASPGIQIRDEHGTAHTSVL-HGNDAVSVTSSINFYFGSGRTGRRTGVIFNNA 441
             |..::.:||||  :|     |:.||||.||: ....|||.||:||.||||......:|::|||.
Human   363 THPISYYKPEFY--TP-----DDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNE 420

  Fly   442 MSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIVTERATGNVRLVVGAAGGTKIISALSP 506
            |.|||...:.|.|.:|..| .|.:.|..:|:|||||.|:..: .|.||:||||||||:|.:|.:.
Human   421 MDDFSSPSITNEFGVPPSP-ANFIQPGKQPLSSMCPTIMVGQ-DGQVRMVVGAAGGTQITTATAL 483

  Fly   507 LLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYGLRQSYVDSLAERGHRCERYENRGSVICGIA 571
            .::..||....:|.|::..|:|:|:||||...|..:.|:...:|..|.|..:......:|:..|.
Human   484 AIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIV 548

  Fly   572 QANDTIWVNSDFRKPGGVSGF 592
            :........||.||.|..:|:
Human   549 RTAGGWAAASDSRKGGEPAGY 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1492	NP_572774.1	G_glu_transpept	74..587	CDD:425991	197/530 (37%)
GGT1	NP_038265.2	G_glu_transpept	55..564	CDD:425991	197/530 (37%)