DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1492 and Ggt7

DIOPT Version :9

Sequence 1:	NP_001303553.1	Gene:	CG1492 / 32164	FlyBaseID:	FBgn0030361	Length:	592	Species:	Drosophila melanogaster
Sequence 2:	NP_001349827.1	Gene:	Ggt7 / 207182	MGIID:	1913385	Length:	666	Species:	Mus musculus

Alignment Length:	555	Identity:	155/555 - (27%)
Similarity:	250/555 - (45%)	Gaps:	58/555 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 FSRAAICSDSDVCSQLAKKVLENGGSAVDGALAALICNGLIGMQSMGIGGGMVMNVYVAKENKSY 121
            |.:.|:.:|:..|:.|..:||...||:||.|:||.:|.|::...|.|:|||.||.|:..:.|:|:
Mouse   137 FQQGAVVTDASSCTALGMEVLSKQGSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRNESH 201

  Fly   122 SILAREMAPLALRADNFSSFRDEQDFKRSGWSIAVPAELAGYAVAHQRFGRLKWKDLVLPTLELC 186
            .|..||.||.|||.:......|.:.....|..:.||..:.|...|||.:|||.|..::.....:.
Mouse   202 LIDFRESAPGALREEALQRSWDTKVGTLPGLLVGVPGMVKGLHEAHQLYGRLPWSQVLAFAAAVA 266

  Fly   187 RRGYRLYKHQYDALILNQDMIRADSGLRRMFIDPDTGRFWPLGH-------LIRPAAQLCNTYDR 244
            :.|:.:......||   .:.:..::..|  |:|    .|.||||       |.||  .|....|.
Mouse   267 QDGFNVTHDLAHAL---AEQLPPNASDR--FLD----TFLPLGHPPLPGSLLRRP--DLAEVLDI 320

  Fly   245 LANEGPLSFYR-GSIADDLLADLKDAGSAITKEDLNQAHAKLSSAIVMPLDEYDLHLT---PPPG 305
            |...||.:||. |::..:::|:.:.||..||:||.:...|.....:   ...|..||.   |||.
Mouse   321 LGTSGPAAFYNGGNLTLEMVAEAQHAGGVITEEDFSNYSALTEKPV---CGVYRGHLVLSPPPPH 382

  Fly   306 SGHVLGFIMNILKEFRAEFSRAGTMSPRQ-IHLMVEAMKFGFVKRWQLD----ESASEELLSNLT 365
            :|..|...:|||:    .|:....:|..| :|.:.|.:|.......:|.    :|...|.:.::.
Mouse   383 TGPALISALNILE----GFNLTSLVSREQALHWVAETLKIALALASRLGDPVYDSTITESMDDML 443

  Fly   366 SHELAKSVARQINHTHTFNRP-----EFYGASPGIQIRDEHGTAHTSVLHGND--AVSVTSSINF 423
            |...|.:....|:.:.....|     |..||....|:          ::.|.|  .|::.||:|.
Mouse   444 SKVEAANFRGHISDSQAAPAPLLPVYELDGAPTAAQV----------LVMGPDDFIVAMVSSLNR 498

  Fly   424 YFGSGRTGRRTGVIFNNAMSDFSIEQLKNYFDLPFVPGTNGVAPAARPMSSMCPVIV--TERATG 486
            .||||.. ..:|::.|:.|.|||..........|.:  .|.|.|..||:|.:.|.:|  .|...|
Mouse   499 PFGSGLL-TPSGILLNSQMLDFSWPNRTANHSAPSL--ENSVQPGKRPLSFLLPTVVRPAEGLCG 560

  Fly   487 NVRLVVGAAGGTKIISALSPLLVRILWQEASIKAAIDASRIHHQMLPNVLLYEYGLRQSYVDSLA 551
            .. |.:||.|..:.:|.|:.:|:.:|....::..::...|:|..:..|:|..:....:..::.|.
Mouse   561 TY-LALGANGAARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDLQSNLLQVDSEFTEEEIEFLE 624

  Fly   552 ERGHRCERYENRGSVICGIAQANDTIWVNSDFRKP 586
            .|||..|:.:.. |.:.|..:.|..|....|.|.|
Mouse   625 ARGHHVEKVDVL-SWVHGSRRTNTFIIGVKDPRSP 658

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1492	NP_001303553.1	G_glu_transpept	76..587	CDD:279371	150/536 (28%)
Ggt7	NP_001349827.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	26..90
Ggt7	NP_001349827.1	G_glu_transpept	155..658	CDD:307247	149/535 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910