Protein Alignment fw and svep1

DIOPT Version :10

• Sequence 1: NP_511136.2
• Gene: fw / 32162
• FlyBaseID: FBgn0001083
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: NP_001429572.1
• Gene: svep1 / 567357
• ZFINID: ZDB-GENE-110726-1
• Length: 3615
• Species: Danio rerio
• Alignment Length: 1111
• Identity: 294/1111 - (26%)
• Similarity: 418/1111 - (37%)
• Gaps: 232/1111 - (20%)

  Fly    58 CGPPAV------PLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNV 116
            ||.|.|      .||.|:...|:.       |.|..||.|.|...::|:....|....|.| ..|
Zfish  1905 CGEPPVVDYAEYTLNGKIYRSTLS-------YTCIEGYRLQGAMELQCESSGEWTSPPPMC-ARV 1961

  Fly   117 AYRKP-------VNQSSYTRSGPASY-ANDG------------KPGNKNPDGQECSETQKEPSPW 161
            ...||       :...::|......| ..||            ..||...:..:|......|.|
Zfish  1962 DCGKPPPLKDAVIKGDNFTLGSKIYYICKDGYTLLGAETQECLPSGNWTRNSSQCVPRSCGPPP- 2025

  Fly   162 WRVDLLTPQAVHVVRITTRGCCGHQPLQDLEI-------RVGNSSADLQRNPLCAWYPGTLDEG- 218
             :||...|..            |||...|:.|       ..||:: .|..|....|.|   .:|
Zfish  2026 -QVDHALPDT------------GHQLFGDIAIYFCDDGYTAGNNT-KLFCNAQGVWAP---PDGF 2073

  Fly   219 ----VVKTFTCARPLVGQYVAIQLVGVEGSLSLCEV-----ETFTNDEFSVDRCLSPKIGVDTVV 274
                .:..| |.||....:..:..:......|..||     |.|..:.....:||   ||.:...
Zfish  2074 GIPHCIANF-CQRPPDLPHAILDSINKPKYASNTEVSYKCEEGFVLNTTGTLKCL---IGGEWTP 2134

  Fly   275 TTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQ 339
            :.....|.....:|.||.:|........|...|..:......:|..|   :|...|....|.|..
Zfish  2135 SPSDIGCMPVRCSKPESIEKGYVSGNNYGFGAVIAYSCDKGYFIRGE---KKRICKASGEWGGVL 2196

  Fly   340 K--EPGITSRTWKWVNGDVVQKPTWGKDQPNN--YNGEQNCVVLDGGR-----------NWLW-- 387
            .  :|.......:..||.:     .|:.:.|:  ||.:......||.|           |..|
Zfish  2197 PTCQPISCPSPPRLANGFI-----QGQIRKNSYVYNSKVTYACNDGYRLTGKPERTCMANKQWSN 2256

  Fly   388 -NDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTEREC--- 448
             |.:.|.|           |:|.:|...:|....|..|.:|.|:::.|.:|:.|:|.|...|
Zfish  2257 SNSLVCVL-----------LTCPTPPDIKNGLYHGSTFEVGSKVEFVCNEGYELIGDTVWTCLKF 2310

  Fly   449 -----------------------------RLD---GT------------------------WSGS 457
                                         .||   ||                        |:.|
Zfish  2311 GNWDKSIIPRCSPVQCPEPPLEENHLVLRGLDSDSGTVELSCEEGYVLHGARTLRCTPSQEWNDS 2375

  Fly   458 SPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDG-WSGKQPECL 521
            .|.||.|.||..||:.||.  .|:.::.||.|.||||.:.:||....:..|..:| ||...|:|:
Zfish  2376 FPVCKQVFCGPPPEVAFGD--PSDTQSYFGSVVTYSCMDGFTLRKEGSVHCQANGNWSKPYPQCI 2438

  Fly   522 VDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAP 586
            ...||.|:.|..|.|........|||.|.|:.||.::|.:.:.||..|:|....|.|..|.|.||
Zfish  2439 PVECPHPEDIPNGIVDVQGLMYLSTAVYSCKAGYDILGNSTVLCGQSGQWIGGIPVCHPVKCAAP 2503

  Fly   587 ARPNRGIAILLNGTTTVNSV-----VKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETP 646
            ..       :.||:...:.:     :.|.|...:.:.|...|.|...|:|..|||.|..:.|..|
Zfish  2504 KE-------IPNGSVRYSKLQFSQSITYFCQRGYRIQGPETLTCLENGQWDQEAPTCVPIYCSPP 2561

  Fly   647 SVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYG- 710
            ......||.|.|......|.|:|.||.::.|...|.|.|.| ||:..|.|...|||....|.:|
Zfish  2562 KPIDNGFVEGRDRKFGVTIFYSCFPGFLLVGNNHLTCEDHG-WSSSEPKCVLADCGLPPHIDFGD 2625

  Fly   711 -------SHKY---------VTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEI 759
                   |.:|         |.|:...||.|.:.|...::::|.:...|.|...|:..:|.|...
Zfish  2626 YSKVQELSAEYDMVTSQQLPVDNSFLHGSLVKYHCHSGYEINGAIMLMCREDGTWNGTAPMCTPA 2690

  Fly   760 RCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCT 824
            :|..|....:..:.||.:                      .:|:||:|.|..||::.|:.:..|.
Zfish  2691 QCEAPPSPENGSVMVTDS----------------------ALGSLAEYSCAEGYELNGQTIRQCI 2733

  Fly   825 DSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNW 889
            ...|||...|.|:.:.||.|.||.||:|:  ..:.::...:.|||:..|.|.||..|.|...|.|
Zfish  2734 SGQQWSDDAPRCLPISCGNPGGIANGEVI--GKSFHFKELIHYECHSGFVLEGVETRTCQVDGKW 2796

  Fly   890 SHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTC 954
            .::||.|.||.|..|.::::::|.......|....|.|..|.|::|..|.||..||.|....|.|
Zfish  2797 DNKAPLCKEVSCGRPVVSKDVLVRGDDHTFGKRLLFSCNLGFILLGAPTIVCLANGSWNEVPPKC 2861

  Fly   955 RPVDCGRPLAIENGRVIVVNDSTLYG--GSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELA 1017
            .|.:||:|.:||||||    ..|.||  |...|.|...|...|.....|..||.|....|||::.
Zfish  2862 LPANCGQPPSIENGRV----TGTDYGYNGMVRYACDIGYVLTGNPTLICRADGLWDDPPPRCDII 2922

  Fly  1018 TAEGQE 1023
            |.:..|
Zfish  2923 TCDPPE 2928

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_511136.2	CCP	58..112	CDD:153056	17/59 (29%)
		FTP	113..261	CDD:128870	36/184 (20%)
		CLECT	281..403	CDD:153057	28/139 (20%)
		PHA02927	<408..578	CDD:222943	64/229 (28%)
		PHA02927	<508..696	CDD:222943	62/193 (32%)
		PHA02639	643..>837	CDD:165022	56/210 (27%)
		PHA02927	798..1014	CDD:222943	78/217 (36%)
svep1	NP_001429572.1	None