DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fw and csmd1a

DIOPT Version :9

Sequence 1:	NP_001285146.1	Gene:	fw / 32162	FlyBaseID:	FBgn0001083	Length:	1174	Species:	Drosophila melanogaster
Sequence 2:	NP_001017855.1	Gene:	csmd1a / 550553	ZFINID:	ZDB-GENE-050417-402	Length:	264	Species:	Danio rerio

Alignment Length:	302	Identity:	68/302 - (22%)
Similarity:	95/302 - (31%)	Gaps:	124/302 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 VNGDVVQKPTWGKDQPNNYNGEQNC--VVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQ 414
            :|| .::.|.:    |:.|....||  :::.|.||.:         .|:|   |:
Zfish    30 LNG-TIESPGF----PHGYPNYANCTWIIVTGERNRI---------QLYF---HT---------- 67

  Fly   415 QNTTVMGKKFTLGEKIQYTC-----PKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKF 474
                     |.|.|......     |:..:|      :.||.| :...||   .|..||:..|.|
Zfish    68 ---------FALEEDFDIVSIYDGQPQPGNL------KMRLSG-FMLPSP---IVSSGSILALWF 113

  Fly   475 GSIHMSEERTSF-----GVVATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDWCPDPQPIAGG 534
                    .|.|     |..|.|....::|                         |.:|..|..|
Zfish   114 --------TTDFAVSAQGFKAIYEVLPSHT-------------------------CGNPGLIPRG 145

  Fly   535 DVRFNDKRAGSTATYVCEPGYVLVGEAIISC----GLGGEWSSKTPSCRFV-DCGAPARPNRGIA 594
            .:.......|....|.|..||||.|..:::|    |.|..|....|.||.. .||.
Zfish   146 IIHGTRYNVGDKIRYSCVMGYVLEGHGVLTCIVSPGSGASWDFPVPFCRVEGSCGG--------- 201

  Fly   595 ILLNGTT-TVNS---VVKYECDEDHWLDGQSELYCTREGKWS 632
             .|.||| |::|   ..:||.:.|          ||    ||
Zfish   202 -TLRGTTGTISSPHFPSEYENNAD----------CT----WS 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_001285146.1	CCP	58..112	CDD:153056
		FTP	113..261	CDD:128870
		CLECT	281..403	CDD:153057	12/52 (23%)
		CCP	408..462	CDD:153056	10/58 (17%)
		CCP	466..520	CDD:153056	10/58 (17%)
		CCP	525..579	CDD:153056	17/57 (30%)
		CCP	583..639	CDD:153056	15/54 (28%)
		PHA02927	637..897	CDD:222943
		CCP	643..697	CDD:153056
		CCP	701..757	CDD:153056
		Sushi	<799..836	CDD:278512
		Sushi	841..896	CDD:278512
		CCP	901..955	CDD:153056
		CCP	959..1015	CDD:153056
csmd1a	NP_001017855.1	CUB	23..130	CDD:238001	33/153 (22%)
		CCP	136..193	CDD:214478	17/56 (30%)
		CUB	210..>255	CDD:214483	8/33 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BCEG
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900