DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fw and Cfhr2

DIOPT Version :9

Sequence 1:NP_001285146.1 Gene:fw / 32162 FlyBaseID:FBgn0001083 Length:1174 Species:Drosophila melanogaster
Sequence 2:NP_001020746.1 Gene:Cfhr2 / 545366 MGIID:3611575 Length:332 Species:Mus musculus


Alignment Length:376 Identity:85/376 - (22%)
Similarity:129/376 - (34%) Gaps:124/376 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   583 CGAPARPNRGIAILLNGTTTVNSV-------VKYECDEDHW-LDGQSELYCTREGKWSGEAPVCE 639
            |..|        .:|||..|.:.:       ::|||:...: :.|.:...||..| |. ..|.|.
Mouse    28 CSPP--------YILNGIYTPHRIIHKSDDEIRYECNYGFYPVTGSTVSKCTPTG-WI-PVPRCT 82

  Fly   640 LVTCETPSVPSG------SFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYC-E 697
            |..||.|....|      |....:..::.:|..|.||.|                :|..:.|. :
Mouse    83 LKPCEFPQFKYGRLYYEESLRPNFPVSIGNKYSYKCDNG----------------FSPPSGYSWD 131

  Fly   698 YIDCGTILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCP 762
            |:.|                 |..|.|....|          .|.|:...|.:..|...|:|   
Mouse   132 YLRC-----------------TAQGWEPEVPC----------VRKCVFHYVENGDSTYWEKI--- 166

  Fly   763 EPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMV-GEALATCTDS 826
                                                |..|...|.:|..||.:. |:...|||::
Mouse   167 ------------------------------------YVQGQSLKVQCYNGYSLQNGQDTMTCTEN 195

  Fly   827 GQWSGTIPECVYVE----CGAPEGINNGKVVLATNATYYG-AAVLYECNVNFKLNGVSRRLCTEH 886
            | ||.. |:|:.:.    ||.|..|:||.:...:...|.. ::|.|:|...:.|.| ::.:...:
Mouse   196 G-WSPP-PKCIRINSTRTCGPPPPIDNGDITSLSLPEYEPLSSVDYQCQKYYLLKG-NKTITCRN 257

  Fly   887 GNWSHEAPECVEVVCDTPNINE--NLIV-----EAGPRAVGSVATFKCAKG 930
            |||| |.|.|:.......||.|  |:|:     |......|....|:|.:|
Mouse   258 GNWS-EPPMCLHACVIPENIMEAHNIILKWRHTEKIYAHSGEDIEFECKRG 307

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fwNP_001285146.1 CCP 58..112 CDD:153056
FTP 113..261 CDD:128870
CLECT 281..403 CDD:153057
CCP 408..462 CDD:153056
CCP 466..520 CDD:153056
CCP 525..579 CDD:153056
CCP 583..639 CDD:153056 15/63 (24%)
PHA02927 637..897 CDD:222943 59/272 (22%)
CCP 643..697 CDD:153056 12/60 (20%)
CCP 701..757 CDD:153056 9/55 (16%)
Sushi <799..836 CDD:278512 14/37 (38%)
Sushi 841..896 CDD:278512 18/55 (33%)
CCP 901..955 CDD:153056 10/37 (27%)
CCP 959..1015 CDD:153056
Cfhr2NP_001020746.1 CCP 28..81 CDD:153056 15/62 (24%)
CCP 155..204 CDD:153056 18/89 (20%)
CCP 212..266 CDD:153056 18/55 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
10.960

Return to query results.
Submit another query.