Protein Alignment fw and Csmd2

DIOPT Version :10

• Sequence 1: NP_511136.2
• Gene: fw / 32162
• FlyBaseID: FBgn0001083
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_063144694.1
• Gene: Csmd2 / 313040
• RGDID: 1565728
• Length: 3640
• Species: Rattus norvegicus
• Alignment Length: 1192
• Identity: 281/1192 - (23%)
• Similarity: 420/1192 - (35%)
• Gaps: 359/1192 - (30%)

  Fly    56 QICGPPAVPLNAKVR--TITVDSQIAEAHYECDAGYELFGPSAVKCDRRT--GWDRDLPF----C 112
            |.|..|....|..||  ...|...:.   :||..||:|.|...:.|...|  .||..||.    |
  Rat  2152 QECPDPEPFANGIVRGAGYNVGQSVT---FECLPGYQLTGQPVLTCQHGTNRNWDHPLPRCEVPC 2213

  Fly   113 GVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVH---- 173
            |.|:.   ..|.:.|:...|:.|::          .|:|.         |::.:.....||
  Rat  2214 GGNIT---SFNGTVYSPGYPSPYSS----------SQDCV---------WQITVPIGHGVHLNLS 2256

  Fly   174 VVRITTRGCCGHQPLQD-LEIRVGNSSADLQ-----------------RNPLCAWYPGTLDEGVV 220
            :::|        :|..| :.:..|.....||                 ...|..::..|...|:.
  Rat  2257 LLQI--------EPFGDYITVWDGPQQTSLQLGVFTRSLSKKIAYSSSNQVLLKFHRDTATGGIF 2313

  Fly   221 K-TFT------CARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVD-----RCLSPKIGVDTV 273
            . .||      |..|.:              |...||.| .|:||::.     |||.....|.:.
  Rat  2314 AIAFTAYPLTKCPPPTI--------------LPNAEVVT-ENEEFNIGDIVRYRCLPGFTLVGSE 2363

  Fly   274 VTTFSKTCYDFHITKGESFDKAQAICK-----------QTGGDLVHDFRGA-------------- 313
            :.|.....|       ..|:....||:           .||..|...:.|:
  Rat  2364 ILTCKLGTY-------LQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVE 2421

  Fly   314 -------TSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYN 371
                   |..|.|||.:..:.|:                      .:|...|.|.. |....||:
  Rat  2422 PEYNVSITVEYFLSEKQYDEFEI----------------------FDGPSGQSPLL-KALSGNYS 2463

  Fly   372 ------GEQNCVVLDGGRNWLWNDVGCNLDY---------------------------LHF---- 399
                  ...|.|.|....:..:|..|..:.|                           :||
  Rat  2464 APLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPKAPLHGFILGQTTTQPGGSIHFGCNT 2528

  Fly   400 ----------ICQHSP---------------LSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHS 439
                      ||...|               :|||.|.|.:|..|.||::|:|.|..|:|.:|:.
  Rat  2529 GYRLVGHSMAICTRHPQGYHLWSEAIPLCQAISCGLPAAPKNGIVFGKEYTVGTKAVYSCNEGYH 2593

  Fly   440 L---------------------------------------------------------------- 440
            |
  Rat  2594 LQTGAEATTECLDTGLWSNSNVPPQCVPVTCPDISSISVEHGRWRLIFETQYQFQAQLMLICDPG 2658

  Fly   441 ---LGQTERECRLDGTWS--GSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTL 500
               .||....|:.:|.||  .|.|||:.:.||.||....|  |.....:.:|..|.:||:..|||
  Rat  2659 YYYTGQRVIRCQANGRWSLGESMPTCQIISCGELPTPPSG--HRIGTMSVYGATAIFSCNSGYTL 2721

  Fly   501 IGNENRTCAMDG-WSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIIS 564
            :|:..|.|..:| |||.:..||...|..|:||..|.:...:.....:..|.|..|:.|:|.::..
  Rat  2722 VGSRVRECMSNGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRI 2786

  Fly   565 CGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTT-----TVNSVVKYECDEDHWLDGQSELY 624
            |.....||.|||.|..:.||.|..|       :||.|     .:|.|||:.|:..:..:|.:...
  Rat  2787 CQQDHHWSGKTPFCVPITCGHPGNP-------VNGLTQGSQFNLNDVVKFVCNPGYMAEGAARSQ 2844

  Fly   625 CTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYN----VHSK----------IQYNCDPGHIM 675
            |...|:||...|.|.::.|..|         |:..|    ||:.          :.|.|:.|..:
  Rat  2845 CLASGQWSDTLPTCRIINCTDP---------GHQENSVRQVHASGPHRFSFGTTVSYQCNHGFYL 2900

  Fly   676 HGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGS--HKYVTNTTY-VGSEVVFSCSQSHKLSG 737
            .|.|.|.|...|.|....|.|..:.||.    | ||  |..::..:| ||:.|.:||:....|.|
  Rat  2901 LGAPALSCQGDGTWDRPRPQCLLVSCGH----P-GSPPHAQMSGDSYIVGAVVRYSCTGKRTLVG 2960

  Fly   738 VLKRTCLESAVWSDASPKCEEIR---CPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTY 799
            ...|.|.....|:.:.|.|....   |.:|.:.||.               ||..:|       :
  Rat  2961 NATRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHG---------------IRLGDS-------F 3003

  Fly   800 KIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAA 864
            ..|:|.::.||.|:.:.|.:...|..:|.|||:.|||..:.||.|...:|.:||. ::...:.::
  Rat  3004 APGSLIRFSCEAGHMLRGSSERVCQANGSWSGSQPECGVISCGNPGTPSNARVVF-SDGLVFSSS 3067

  Fly   865 VLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAK 929
            ::|||...:...|:..|.|:.:|.|:...|||..:.|..|.|..|.|............|::|..
  Rat  3068 IVYECREGYYSTGLLSRHCSVNGTWTGSDPECTVINCGDPGIPANGIRLGNDFRYNKTVTYQCVP 3132

  Fly   930 GRIMMGNDTRV--CQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYN 992
            |.:|......|  |.|:..|.|..|.|:.:.|..|..|.||:| |.:|.| :|.|..|.|:..|.
  Rat  3133 GYVMESRRVSVLGCTKDRTWNGTKPVCKAIMCKPPQLIPNGKV-VGSDFT-WGSSVSYACLEGYQ 3195

  Fly   993 RIGQYLRKCTEDGAWSGKQPRC 1014
            .....:..|..:|:|:|:.|:|
  Rat  3196 LSLPAVLTCEGNGSWTGELPQC 3217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_511136.2	CCP	58..112	CDD:153056	18/61 (30%)
		FTP	113..261	CDD:128870	31/176 (18%)
		CLECT	281..403	CDD:153057	30/200 (15%)
		PHA02927	<408..578	CDD:222943	63/239 (26%)
		PHA02927	<508..696	CDD:222943	59/207 (29%)
		PHA02639	643..>837	CDD:165022	56/213 (26%)
		PHA02927	798..1014	CDD:222943	66/217 (30%)
Csmd2	XP_063144694.1	None