DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fw and Cfhr1

DIOPT Version :9

Sequence 1:	NP_001285146.1	Gene:	fw / 32162	FlyBaseID:	FBgn0001083	Length:	1174	Species:	Drosophila melanogaster
Sequence 2:	NP_001037692.1	Gene:	Cfhr1 / 289057	RGDID:	1310510	Length:	274	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	69/264 - (26%)
Similarity:	110/264 - (41%)	Gaps:	52/264 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 SSPTCKYVDCGSLPELKFGSIHMSEERTSF-----GVVATYSCHENYT---------LIGNENRT 507
            ||...:.:.| ..|:::.|.::..::...|     |.:..|||..|:.         :|
  Rat    19 SSAKGEGIHC-DFPKIRHGIVYDEKKYEPFSPVPGGKILYYSCEYNFASPSSSFWNPII------ 76

  Fly   508 CAMDGWSGKQPECL-VDWCPDPQ---PIAGGDVRFNDKRAGSTATYVCEPGYVLV-GEAIISCGL 567
            |...||| ..|:|| :.:.|..:   ..:.|...    :.|.....||..||.|. .::.|:||.
  Rat    77 CTEAGWS-PVPKCLRICFFPSVENGHSTSSGQTH----KEGDIVQIVCNQGYSLQNNQSTITCGE 136

  Fly   568 GGEWSSKTPSCRFVD----CGAPARPNRG-IAILLNGTTTVNSVVKYECDEDHWLDGQSELYCTR 627
            .| ||. .|.|...:    ||.|...:.| |..|........|.|:|:|.....|.|...:.| |
  Rat   137 EG-WSI-PPKCISPNSAGKCGPPPSIDNGDITSLSLPEYAPLSSVEYQCQNYFLLKGNKIITC-R 198

  Fly   628 EGKWSGEAPVCELVTCETPS--VPSGSFVIGYDYN--VHSK----IQYNCDPGH-IMHGTPVL-- 681
            .|||| :.|.| |..|..|.  :...:.|:.:..|  ::|:    |::.|.||: .:.|:|..
  Rat   199 NGKWS-DPPTC-LHACVIPEDILEKHNIVLRWRENGRIYSQSGENIEFMCKPGYRKLRGSPPFRS 261

  Fly   682 ECLD 685
            :|:|
  Rat   262 KCID 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_001285146.1	CCP	58..112	CDD:153056
		FTP	113..261	CDD:128870
		CLECT	281..403	CDD:153057
		CCP	408..462	CDD:153056	2/4 (50%)
		CCP	466..520	CDD:153056	15/67 (22%)
		CCP	525..579	CDD:153056	15/57 (26%)
		CCP	583..639	CDD:153056	19/56 (34%)
		PHA02927	637..897	CDD:222943	15/60 (25%)
		CCP	643..697	CDD:153056	13/54 (24%)
		CCP	701..757	CDD:153056
		Sushi	<799..836	CDD:278512
		Sushi	841..896	CDD:278512
		CCP	901..955	CDD:153056
		CCP	959..1015	CDD:153056
Cfhr1	NP_001037692.1	CCP	95..146	CDD:153056	15/56 (27%)
Cfhr1	NP_001037692.1	CCP	154..208	CDD:153056	19/55 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960