DRSC/TRiP Functional Genomics Resources

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Protein Alignment fw and Selp

DIOPT Version :10

Sequence 1:NP_511136.2 Gene:fw / 32162 FlyBaseID:FBgn0001083 Length:1174 Species:Drosophila melanogaster
Sequence 2:NP_037246.2 Gene:Selp / 25651 RGDID:3656 Length:768 Species:Rattus norvegicus


Alignment Length:824 Identity:198/824 - (24%)
Similarity:293/824 - (35%) Gaps:207/824 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   287 TKGESFDKAQAICKQTGGDLV-----------HDFRGATSSYILSELERRKSELKPQLVWIGAQK 340
            ||..|::.::|.||:...|||           :|.....:||                .|||.:|
  Rat    48 TKAYSWNNSRAFCKRHFTDLVAIQNKNEIAHLNDVIPYVNSY----------------YWIGIRK 96

  Fly   341 EPGITSRTWKWVNGD---VVQKPTWGKDQPNNYNGEQNCV---VLDGGRNWLWNDVGC--NLDYL 397
                .:..|.||..:   ..:...|..::|||....|:||   :........|||..|  ....|
  Rat    97 ----INNKWTWVGTNKTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAPGKWNDEPCFKRKRAL 157

  Fly   398 HFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQ----YTCPKGHSLLGQTERECRLDGTWSGSS 458
            .:......:||.|.               ||.|:    |||.......|                
  Rat   158 CYTASCQDMSCNSQ---------------GECIETIGSYTCSCYPGFYG---------------- 191

  Fly   459 PTCKYV-DCG--SLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDG-WSGKQPE 519
            |.|:|| :||  .:|:....:........||....|:||.|.|.|.|.....|...| |:...|:
  Rat   192 PECEYVQECGKFDIPQHVLMNCSHPLGDFSFSSQCTFSCPEGYDLNGPSEMQCLASGIWTNNPPQ 256

  Fly   520 CLVDWCPDPQPIAGGDVRFNDKRAG----STATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRF 580
            |....|...:....|.:......|.    |:..:.|:|||.:.|..|:.|...|:||...|:|..
  Rat   257 CKAVQCQSLEAPLHGTMDCTHPLAAFAYDSSCKFECQPGYRMRGSDILHCTDSGQWSEPLPTCEA 321

  Fly   581 VDCGAPARPNRGI--AILLNGTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTC 643
            :.|.....|..|.  .....|....||...:.|.|...|.|...::|...|:|:..|||||.:.|
  Rat   322 IACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFVLMGNDAIHCADLGQWTAPAPVCEALQC 386

  Fly   644 ETPSVPSGSFVIGYD----YNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDC--- 701
            :...|||.:.|...|    ....|...::||.|.::.|..|:.||.:|.||...|.|:.:.|   
  Rat   387 QEFPVPSKAQVSCSDPFGTLKYQSACSFSCDEGSLLVGASVIRCLATGHWSEAPPECQAVSCTPL 451

  Fly   702 -----GT---ILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEE 758
                 ||   |.|:.:.::|         |...|.|.:...|||..:..|..|..|:.:.|.||.
  Rat   452 LSPENGTMTCIQPLGHSNYK---------STCQFMCDEGFYLSGPERLDCSPSGHWTGSPPMCEA 507

  Fly   759 IRCPE---PKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEAL 820
            |:|||   |:..:.....|.|.                     :.:|:...:.|...::::|...
  Rat   508 IKCPEIFAPEQGSLDCSHVHGE---------------------FSVGSTCHFSCNEEFELLGSRN 551

  Fly   821 ATCTDSGQWSGTIPECVYVECGAPEGINNGKV------VLATNATYYGAAVLYECNVNFKLNGVS 879
            ..||.||:||...|.|        :|:.:..|      .|.|                   .|..
  Rat   552 VECTVSGRWSAPPPTC--------KGVTSLPVPSVRCPALTT-------------------PGQG 589

  Fly   880 RRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKN 944
            ...|..|                        :...||   .:...|.|..|..:.|.::..|..:
  Rat   590 TMSCRHH------------------------LESFGP---NTTCYFGCKTGFTLRGANSLRCGAS 627

  Fly   945 GKWTGKSPTCRPVDCGRPLAIENGRVIVVNDST-----LYGGSAEYHCIPNYNRIGQYLRKCTED 1004
            |:||..:|.||.|.|..   :.....:.:|.|.     .||.:..:||....:..|.....|.||
  Rat   628 GQWTAVTPVCRAVKCSE---LHMDTAVAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCRED 689

  Fly  1005 GAWSGKQPRCELATAEGQET-SELG------TGVGIGATVIVAL 1041
            |.||...|.|:..|...||. :.||      ||:.:|.|::..|
  Rat   690 GHWSDAMPTCQAGTLTIQEALTYLGGALASTTGLAVGGTLLALL 733

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fwNP_511136.2 CCP 58..112 CDD:153056
FTP 113..261 CDD:128870
CLECT 281..403 CDD:153057 31/134 (23%)
PHA02927 <408..578 CDD:222943 45/181 (25%)
PHA02927 <508..696 CDD:222943 57/198 (29%)
PHA02639 643..>837 CDD:165022 54/211 (26%)
PHA02927 798..1014 CDD:222943 47/226 (21%)
SelpNP_037246.2 CLECT_selectins_like 42..160 CDD:153062 31/131 (24%)
EGF_CA <168..195 CDD:238011 10/57 (18%)
CCP 200..258 CDD:153056 16/57 (28%)
PHA02927 276..505 CDD:222943 67/237 (28%)
PHA02927 443..699 CDD:222943 73/342 (21%)
Endocytosis signal. /evidence=ECO:0000305 756..759
Interaction with SNX17. /evidence=ECO:0000250 759..768
Blue background indicates that the domain is not in the aligned region.

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