DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fw and Cr1l

DIOPT Version :9

Sequence 1:	NP_001285146.1	Gene:	fw / 32162	FlyBaseID:	FBgn0001083	Length:	1174	Species:	Drosophila melanogaster
Sequence 2:	NP_038527.2	Gene:	Cr1l / 12946	MGIID:	88513	Length:	440	Species:	Mus musculus

Alignment Length:	399	Identity:	104/399 - (26%)
Similarity:	168/399 - (42%)	Gaps:	69/399 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   721 VGSEVVFSCSQSHKLSGVLKR----TCLESAVWSDASPKCEEIRCPEPKLAAHSLLSV-TGNDRM 780
            :|:.:::.|     |.|.:||    ||.:.:.|:.|..||...:|..|....:.|:.| ||
Mouse    64 IGTYLLYEC-----LPGYIKRQFSITCKQDSTWTSAEDKCIRKQCKTPSDPENGLVHVHTG---- 119

  Fly   781 YGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATC--TD-SGQWSGTIPECVYVECG 842
                              .:.|:...|.|.:||:::|.:.|.|  || |..|....|.|.::.|.
Mouse   120 ------------------IQFGSRINYTCNQGYRLIGSSSAVCVITDQSVDWDTEAPICEWIPCE 166

  Fly   843 APEGINNGKVVLATNATY-YGAAVLYECNVN------FKLNGVSRRLCT----EHGNWSHEAPEC 896
            .|.||.||....:|...: ||..|.|.||.:      |.|.|.....||    |.|.||...|:|
Mouse   167 IPPGIPNGDFFSSTREDFHYGMVVTYRCNTDARGKALFNLVGEPSLYCTSNDGEIGVWSGPPPQC 231

  Fly   897 VEV-VCDTPNINENLIVEAGPRAVGS---VATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTC-RP 956
            :|: .|..|...||.::.:..|::.|   :..|:|..|.||.|..:..||...||..:.|:| :.
Mouse   232 IELNKCTPPPYVENAVMLSENRSLFSLRDIVEFRCHPGFIMKGASSVHCQSLNKWEPELPSCFKG 296

  Fly   957 VDCGRPLAIEN-GRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAE 1020
            |.|..|..:.. .:.:.:.....||.:....|...|...|....:|..||:|:....:|...:..
Mouse   297 VICRLPQEMSGFQKGLGMKKEYYYGENVTLECEDGYTLEGSSQSQCQSDGSWNPLLAKCVSRSIS 361

  Fly  1021 GQETSELGTGVGIGATVIVALLVIF-GLIFLYRNKARPVKNTENVQAAET------KDERNAAVM 1078
            |     |..|:.||..|.:.::::| .:|..|:.     :||.:.:..|.      |::....:.
Mouse   362 G-----LIVGIFIGIIVFILVIIVFIWMILKYKK-----RNTTDEKYKEVGIHLNYKEDSCVRLQ 416

  Fly  1079 SYSTLEANN 1087
            |..|.:.|:
Mouse   417 SLLTSQENS 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_001285146.1	CCP	58..112	CDD:153056
		FTP	113..261	CDD:128870
		CLECT	281..403	CDD:153057
		CCP	408..462	CDD:153056
		CCP	466..520	CDD:153056
		CCP	525..579	CDD:153056
		CCP	583..639	CDD:153056
		PHA02927	637..897	CDD:222943	55/194 (28%)
		CCP	643..697	CDD:153056
		CCP	701..757	CDD:153056	11/39 (28%)
		Sushi	<799..836	CDD:278512	13/39 (33%)
		Sushi	841..896	CDD:278512	23/65 (35%)
		CCP	901..955	CDD:153056	18/57 (32%)
		CCP	959..1015	CDD:153056	11/56 (20%)
Cr1l	NP_038527.2	PHA02927	42..295	CDD:222943	75/257 (29%)
		Sushi	42..98	CDD:278512	10/38 (26%)
		CCP	103..161	CDD:153056	19/79 (24%)
		CCP	165..232	CDD:153056	23/66 (35%)
		CCP	237..293	CDD:214478	17/55 (31%)
		CCP	<315..356	CDD:153056	9/40 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BCEG
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_102627
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1703
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.800