Protein Alignment fw and LOC1272275

DIOPT Version :10

• Sequence 1: NP_511136.2
• Gene: fw / 32162
• FlyBaseID: FBgn0001083
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_311214.6
• Gene: LOC1272275 / 1272275
• VectorBaseID: AGAMI1_009594
• Length: 2280
• Species: Anopheles gambiae
• Alignment Length: 1203
• Identity: 234/1203 - (19%)
• Similarity: 368/1203 - (30%)
• Gaps: 358/1203 - (29%)

  Fly    49 LCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGY-----ELF---------------- 92
            ||....|.:||...       |.:...|.:......||..|     |:.
Mosquito  1178 LCNGTVGNVCGVGG-------RCVVDPSSLLGYQCVCDENYVGEHCEIALNPCGSAPCYNGGRCV 1235

  Fly    93 --GPSAVKCDRR---TGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNP---DGQ 149
              |.:...|..:   ||.    |.|..   |..|. :|.:.::|.:....||:|..:.|   ||:
Mosquito  1236 SNGSAGFVCHCQPPYTGG----PLCEF---YVDPC-RSDHCKNGGSCVEVDGRPFCECPLGYDGE 1292

  Fly   150 ECSETQKEPSPWWRVDLLTP-------QAVHVVRITTRGC--------CGHQPLQDLEIRVG--- 196
            .|.         ||.|..||       ..|:|....:..|        |..:|...|....|
Mosquito  1293 RCE---------WRKDFCTPNPCEFEGMCVNVDEGYSCACPSGKTGRRCHLEPCDYLPCPAGSMC 1348

  Fly   197 -NSSAD-----------LQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSL---- 245
             |.:.|           ||...|    |.. ...:..::.|..|          ||:.|:.
Mosquito  1349 LNGANDTAAGNDRFTVALQTQQL----PSN-SGSLAYSYRCVCP----------VGLRGTSCAEL 1398

  Fly   246 -SLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHD 309
             :.||...:..:..:.:......:|..|...      ||     .||:.|.:..|..       :
Mosquito  1399 DNPCETSRYCRNGATCEPAKLRVVGASTAED------YD-----DESYRKVRCHCPP-------E 1445

  Fly   310 FRGATSSYILS---ELERRKSELKPQLVWIGAQKEP----GITSRTWKWVN-----GDVVQKPTW 362
            :.|:....:||   |||..::.::..:..:....:.    .|:...|...:     |.::...|.
Mosquito  1446 YHGSRCELLLSAAFELEFPRTGVQAYVKLVADSSDATDLRAISMCGWYRTDDDFNYGTLLSYATA 1510

  Fly   363 GKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLG 427
            ..|...........|:...|.:.:.| |..|....||:|    :|..|...:....|.|::...|
Mosquito  1511 TVDNAFTLTDYSGLVLYVNGAHVVTN-VSLNDGEWHFVC----VSWTSAGGRYVLYVDGERSAYG 1570

  Fly   428 EKIQYTCP---KGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVV 489
            ..:....|   .|..:.||.:     |....|.|.|..|....:..:|....:.:.|
Mosquito  1571 SSLSEGAPIQSGGLYVFGQEQ-----DVLGGGFSETESYRGRMAYVDLWKRELELEE-------- 1622

  Fly   490 ATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDW---------------------CPDPQPIAG 533
                       :|...||||  .:||.    ||.|                     ||....:..
Mosquito  1623 -----------VGRLYRTCA--PYSGD----LVRWIDLRLQTVGLVRIVASSFCRDCPRNHSLPN 1670

  Fly   534 GDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLN 598
            |.||::    |:.|.:.|:.||.|:|.:...|....:|::....|:...||....|..|..:|..
Mosquito  1671 GSVRYD----GTRAVFQCDEGYELIGPSFSECLRTSQWTAGVQFCKLTRCGTIGAPLNGQVLLTK 1731

  Fly   599 GTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVC-ELVTCETPSV---PSGSFVIGY-- 657
              |:.....::.||:...:.|...|:||..|.|||..|.| .:|.| .|.|   ..|...:.|
Mosquito  1732 --TSFGGEARFSCDDGFLIAGAELLHCTARGTWSGPPPDCISIVKC-PPLVLEAHDGRAPVIYAT 1793

  Fly   658 ----------DYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIP---- 708
                      .|:|....:..|.|.:.:....:|.||:||:|....|.|        :|||
Mosquito  1794 ERGVIQQHLDSYDVGVLAEVRCLPEYALTEDNLLTCLESGQWDLPLPEC--------VPIPPTTT 1850

  Fly   709 -----------------------------YGSHK---------------YVTNTTYVGSEVV--- 726
                                         |..|.               |....|..|:...
Mosquito  1851 PEPSRDTQPALIIRVNRRPDVHFWKQLRDYLFHGCTPPAVPGRGLSLFCYSATGTIAGNNWTDLS 1915

  Fly   727 -FSCSQSH--------KLSGVLKRT------------CLESAVWSDASPKCEEIRCP-----EPK 765
             ||..:..        :|.|.|.||            .|...::....|...|:|.|     ..:
Mosquito  1916 GFSLQRDAPRLTNIDVRLLGFLMRTVKPNLNRVVPQNLLHFILYGSVDPIAPEMRYPGHIENAYR 1980

  Fly   766 LAAHSLLSVTGNDR--MYGRTLIRTSESSQNT------------------------AQTYKIGAL 804
            ......:.|...||  .|...|:......:||                        .::.:..|.
Mosquito  1981 FVICQFIDVILMDRELNYDDELVVDIGQEENTNTKIKHLLKNVAHAVYPQYQRLLEERSARESAA 2045

  Fly   805 AKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYY-------- 861
            .|...|...::.|....|.|.:...:.....|......:|.  .:..|.:...||.:
Mosquito  2046 LKKIIELADRVPGSTSTTTTTTTTTAAPPKRCPLSHLPSPP--IDSHVAMVALATLHRPAGEWRL 2108

  Fly   862 ------------GAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEA 914
                        |..:.:.|:..|.:.|.:..:|...|.|:.....|...||:.|....|:::..
Mosquito  2109 EQLLSSGQLADPGDRIQFGCDAGFSMRGSAVTVCGADGRWTMVEGFCEGAVCEHPPTRANMLIAP 2173

  Fly   915 GPR----AVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVND 975
            |.|    .|.....::|..|..:.|:....|..||:||.....|..:.||||..:... .|:...
Mosquito  2174 GSRDKQYYVDDEIEYRCEPGYTIKGHPIVKCLPNGRWTPMVARCTRISCGRPKNLPMA-YILAGS 2237

  Fly   976 STLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWS 1008
            |.|||.|.:..|     |.......|...|.|:
Mosquito  2238 SFLYGDSLKVRC-----RQSSIDITCQSTGQWT 2265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_511136.2	CCP	58..112	CDD:153056	13/79 (16%)
		FTP	113..261	CDD:128870	36/185 (19%)
		CLECT	281..403	CDD:153057	25/133 (19%)
		PHA02927	<408..578	CDD:222943	39/193 (20%)
		PHA02927	<508..696	CDD:222943	57/224 (25%)
		PHA02639	643..>837	CDD:165022	50/311 (16%)
		PHA02927	798..1014	CDD:222943	50/235 (21%)
LOC1272275	XP_311214.6	None