Protein Alignment fw and LOC1272144

DIOPT Version :10

• Sequence 1: NP_511136.2
• Gene: fw / 32162
• FlyBaseID: FBgn0001083
• Length: 1174
• Species: Drosophila melanogaster
• Sequence 2: XP_061500257.1
• Gene: LOC1272144 / 1272144
• VectorBaseID: AGAMI1_004135
• Length: 1157
• Species: Anopheles gambiae
• Alignment Length: 1228
• Identity: 299/1228 - (24%)
• Similarity: 446/1228 - (36%)
• Gaps: 271/1228 - (22%)

  Fly    43 MLLLLALC-------------------AAGNGQI-----CGPPAVPLNAKVRTITVDSQIAE--- 80
            |:|||..|                   .||.|.:     |..|.||.:..|  |..|..:|.
Mosquito    13 MVLLLLSCILLSCTYADEEENFTSASLVAGTGPVASSKGCPFPGVPAHGSV--IFSDDSLANNTV 75

  Fly    81 AHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGN-K 144
            |.|.|:.|:||.|||...|.........:|||.:|||..|...|.|...||....|.||.... .
Mosquito    76 ATYYCERGFELLGPSRRACIDSQWIPEGIPFCVLNVAAGKAPMQISTEASGIPQKAIDGSTSAFF 140

  Fly   145 NPDGQECSETQKEPSPWWRVDLLTPQAVHVVRIT-TRGCCGHQPLQDLEIRVGNSSADLQRNPLC 208
            :||  .||.|:.|..|||.|:||.|..|.:||:. .:.|||......:.:||||:..||..||:|
Mosquito   141 SPD--TCSLTKPERVPWWYVNLLEPYMVQLVRLDFGKSCCGKGKPATIVVRVGNNRPDLGTNPIC 203

  Fly   209 AWYPGTLDEGVVKTFTCARPLVGQYVAIQL-VGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDT 272
            ..:.|:|:||......|..|:.|.:|::.| ......||:||...:|:....::||.:.:.....
Mosquito   204 NRFTGSLEEGQPLFLPCNPPMPGAFVSVHLETNAPSQLSICEAFVYTDQALPIERCPAFRDQPPG 268

  Fly   273 VVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERR-KSELKPQLVWI 336
            ...:::..||.|:..:..:...|.|.|:..||.|:::...|...:|..||.|| :|:...| .|:
Mosquito   269 ASASYNGKCYIFYSRQPATLRDALAFCRARGGTLINESNPALQGFISWELWRRHRSDTSSQ-YWM 332

  Fly   337 GAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFIC 401
            ||.:: .....||||:.|:.|....|     |...|:::|...||.:.|||:|..||.. |:|||
Mosquito   333 GAVRD-AQDRNTWKWIGGEEVSVSFW-----NLPGGDEDCARYDGSKGWLWSDTNCNTQ-LNFIC 390

  Fly   402 QHSPLSCGSPDAQQNTTVMGKK-FTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVD 465
            ||.|.:||.|:...|:|::..| |.:|..::|:|.:||.|:|..:|.|...|.::...|.|||::
Mosquito   391 QHQPKACGRPEQPPNSTMIAPKGFDVGAVVEYSCDEGHLLVGPKQRTCLETGFYNEFPPVCKYIE 455

  Fly   466 CGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMD-GWSGKQPECLVDWCPDPQ 529
            ||....:..|...:......:.....|.|.|.|.::|.....|.:| .|:|..|.|.:..| ||.
Mosquito   456 CGLPASIPHGYYDLVNGTVGYLSTVMYRCAEGYEMVGRAVLICDIDERWNGPPPRCELIEC-DPL 519

  Fly   530 PIA---GGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPA--RP 589
            |..   |..|..|....|:.|...|..|:|...|..|.|...|:||...|.|.......||  ||
Mosquito   520 PTLFPNGVIVSTNQTVYGTRAEVHCNRGFVPDSEPEIVCTASGQWSHPLPKCVPDQSAGPATVRP 584

  Fly   590 ---------NRGIAILLNGTTTVNSV----VKYECDEDHWLDGQSELYCTREGKWSGEAPVCELV 641
                     :|...:|:...||..|:    .:..........|.:..|.|:....|......|..
Mosquito   585 SAASTTPASSRAPPVLIVSPTTPASIGGIPSRARQPTGGRRPGSTVRYPTQAPPASSTVSAAEST 649

  Fly   642 TCE----------------TPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWS 690
            |..                |.:..|..|.|        :|....|..::.||.|..:..|..|..
Mosquito   650 TASIVINMAGPTTAQPSRTTSTTESPLFSI--------EIDDGTDDDYLPHGGPNRKHTDRDEND 706

  Fly   691 ADAPYCEYIDCGTILPIPYGSHKYVTNTTY----------VGSEVVFSCSQSHKLSGVLKRTCLE 745
            .||....|.   ...|..:|.::....|.|          ..:|..|. .....|.|....|..:
Mosquito   707 EDADDDYYY---RNKPNLHGGYRPNAGTDYDDDNDDAHDHHANEPTFD-DNFDSLEGFFIGTNED 767

  Fly   746 SAVWSDASPKCEEIRCP-----------EPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTY 799
            .::.....|...|:| |           .|:..:..:||     :..|.:...:|.||.::....
Mosquito   768 YSLPPPPPPPPSEVR-PGSKGEEAGRPYRPQQPSVVILS-----KEPGSSSSSSSSSSSSSVSKP 826

  Fly   800 KIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAA 864
            .....|.|.......:|.......|...|.:||                .|:.. :|..|..|..
Mosquito   827 ASPKPAVYEPSSPPAVVSVTPQVQTHRPQVTGT----------------TGRRP-STTTTTRGRH 874

  Fly   865 VLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCD-TPNINENLIVEAGPRAVGSVATFKCA 928
            ..:|.::          |.:.|.. .:|.|..|.:..| :|.:|.       |.||.:|.....|
Mosquito   875 PAHEQDI----------LLSHHPQ-DNEIPGSVNIRQDQSPKVNV-------PFAVNNVDDLVPA 921

  Fly   929 KGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNR 993
            .|.         ...||...|.                         .|.:||:.
Mosquito   922 DGS---------SGSNGGTDGL-------------------------ITSFGGAG---------- 942

  Fly   994 IGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFL-------- 1050
                  ..:..|...|..     .:|.|.........:.:||  ||||....|.:||
Mosquito   943 ------GSSGAGGLGGAG-----GSAAGDRKESKNAKLNLGA--IVALGAFGGFVFLAAVITTIV 994

  Fly  1051 ------------YRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFH 1103
                        ||::|.|..||               |.|:|:..:.:|..::......:...|
Mosquito   995 IVVRRNRTSNQHYRHRASPDCNT---------------VASFSSSSSESRNGLNRYYRQAWENLH 1044

  Fly  1104 GGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPY---EMRTNDEVYEP 1158
            ..|                     ::|.|.:..:..::..|||.   ..|.|.:|..|
Mosquito  1045 ESA---------------------SKSHNNHSGLKRKETMDAPVNRSRSRENLDVSRP 1081

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fw	NP_511136.2	CCP	58..112	CDD:153056	19/56 (34%)
		FTP	113..261	CDD:128870	53/150 (35%)
		CLECT	281..403	CDD:153057	42/122 (34%)
		PHA02927	<408..578	CDD:222943	54/174 (31%)
		PHA02927	<508..696	CDD:222943	54/222 (24%)
		PHA02639	643..>837	CDD:165022	41/230 (18%)
		PHA02927	798..1014	CDD:222943	34/216 (16%)
LOC1272144	XP_061500257.1	None