DRSC/TRiP Functional Genomics Resources

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Protein Alignment fw and csmd2

DIOPT Version :10

Sequence 1:NP_511136.2 Gene:fw / 32162 FlyBaseID:FBgn0001083 Length:1174 Species:Drosophila melanogaster
Sequence 2:XP_017947315.2 Gene:csmd2 / 100486627 XenbaseID:XB-GENE-6044604 Length:3598 Species:Xenopus tropicalis


Alignment Length:1219 Identity:292/1219 - (23%)
Similarity:427/1219 - (35%) Gaps:352/1219 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 YECDAGYELFGPSAVKCDRRTGWDRDLPF------CGVNVAYRKPVNQSSYTRSGPASYANDGKP 141
            :||..||.|.|.|.:.|...|..:.|.||      ||.||.   ..|.|.|:...|..|      
 Frog  2137 FECFPGYHLIGHSVLTCQHGTNRNWDHPFPRCEVPCGGNVT---AFNGSIYSPGFPDQY------ 2192

  Fly   142 GNKNPDGQECSETQKEPSPWWRVDLLTPQAVHV--VRITTRGCCGHQPLQD-LEIRVGNSSADLQ 203
                |..|:|         :|.:.:.....:|:  ..:.|      :|..| :.:..|....|.|
 Frog  2193 ----PSSQDC---------YWTITVPLGFGIHINFTILQT------EPQNDYITVWDGPEQTDPQ 2238

  Fly   204 -----------------RNPLCAWYPGTLDEGVVKTF-------TCARP---------------L 229
                             ...|..::....:.|:...:       .|..|               |
 Frog  2239 LGLFTSTSTKRFALSSSNQVLLQFHSDAANAGIFALYFYGYRLRKCKPPITVPNGEVLSGSEEFL 2303

  Fly   230 VGQYV------AIQLVG-------------VEGSLSLCEVETFTNDEFSVDRCLSPKIGV---DT 272
            :|..|      ...|||             .||....|||....|:      .|:...||   .:
 Frog  2304 MGDIVRYKCLPGFTLVGPEILTCRLGNHLLFEGPPPSCEVHCPDNE------ILTDSTGVILSQS 2362

  Fly   273 VVTTFS--KTC-------YDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILS-------E 321
            ...|:.  :||       ..:::|....:..::   ||.....:.|.....|:.::|       .
 Frog  2363 FPGTYPHFQTCSWLIKVESGYNVTLSVEYFLSE---KQYDEFDIFDGPSGQSTLLISLSGNYSAP 2424

  Fly   322 LERRKSELKPQLVWIG--AQKEPGITSRTWK------------WVNGDVVQKP----TWGKDQPN 368
            |....|..|..|.|..  |....|...|.|.            .|.|.|:..|    .:..|...
 Frog  2425 LTITSSGNKVHLRWTSDHAYSRKGFKIRYWALYCSLPRPPLHGTVLGPVINPPGGVVRFNCDPGF 2489

  Fly   369 NYNGEQNCVVLDGGRNWL-WN-DVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQ 431
            ...|......|...:.:. || :|.        :||  .:.||.|.:.:|..|.||::|:|.|..
 Frog  2490 RLIGMNTATCLRRPQGYYDWNSEVP--------LCQ--AMFCGVPASPKNGIVFGKEYTVGTKAM 2544

  Fly   432 YTCPKGHSLLG----------------------------------QTER---------------- 446
            |.|.:||.||.                                  .||.                
 Frog  2545 YECDEGHHLLNPEDAVSECLPSGHWSNGNNPPQCVAITCPDISNLNTEHGRWRIIHKSHYHYGAE 2609

  Fly   447 -----------------ECRLDGTWS--GSSPTCKYVDCGSLPE----LKFGSIHMSEERTSFGV 488
                             .|:.:||||  .::|||..:.||.||.    .|.|.:      |.:|.
 Frog  2610 LMLICDPGYYYVGPRIIRCQANGTWSVGEATPTCNIISCGELPTPANGNKIGML------TQYGA 2668

  Fly   489 VATYSCHENYTLIGNENRTCAMDG-WSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCE 552
            .|.::|:..|||:|:..|.|..:| |||::.:||...|..|:||..|.:...:.....:..|.|.
 Frog  2669 TAIFACNSGYTLVGSRVRECMSNGLWSGQEVKCLAGHCGTPEPIVNGLINEQNYNYRDSVVYQCN 2733

  Fly   553 PGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTT-TVNSVVKYECDEDHW 616
            .|:.|:|.::..|.....||.|.|.|..:.||.|..|..||.   .|:. .:..|||:.|:..:.
 Frog  2734 SGFRLIGMSVRICQQDHLWSGKAPICVPITCGHPGNPGNGIT---QGSQFNLYDVVKFVCNPGYI 2795

  Fly   617 LDGQSELYCTREGKWSGEAPVCELVTCETPS-VPSGSFVI---GYD-YNVHSKIQYNCDPGHIMH 676
            ::|..:..|...|:||...|.|.::.|..|. |..|...:   |.| ::..:.:.|.|..|:.:.
 Frog  2796 IEGSVQAQCQPNGQWSHPMPTCRILNCTDPGHVEYGLRRVLQKGPDRFSFGTSVTYECSHGYYLM 2860

  Fly   677 GTPVLECLDSGEWSADAPYCEYIDCGT--ILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVL 739
            ||.||.|...|.|....|.|..:.||.  :.|....|.|..|    |||.|.:||.....|.|..
 Frog  2861 GTHVLSCQGDGTWDRALPRCLLVTCGAPGLPPNAQISGKRFT----VGSVVQYSCLGRRILIGNA 2921

  Fly   740 KRTCLESAVWSDASPKC---EEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKI 801
            .|||.....||...|.|   ....|.:|.:..|.|                 |:..:.||     
 Frog  2922 TRTCQLDGRWSGFLPHCSGGSAGECGDPGVPFHGL-----------------SQGEEFTA----- 2964

  Fly   802 GALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVL 866
            |::.::.||.||.:.|.|..:|..:|.|.|..|||..|.||.|...:|.:||. .:...:.::::
 Frog  2965 GSVVRFSCEPGYLLRGSAERSCLINGSWGGFQPECEVVSCGNPGTPSNSRVVF-NDGLVFSSSII 3028

  Fly   867 YECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGR 931
            |||...:..:|...|.||.:|.|:..||:|..:.|..|.|..|.:............:|:|..| 
 Frog  3029 YECREGYYSSGPLSRHCTVNGTWTGTAPDCAVINCGDPGIPANGLRLHHDFQYNHTVSFQCLPG- 3092

  Fly   932 IMMGNDTR---VCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNY-- 991
            .||.:|..   :|.|:..|.|..|.|:.:.|..|..|.||:  .|....|:|.|..|.|:..|  
 Frog  3093 YMMESDKAPMLLCTKDRTWNGTKPLCKAITCPSPPVIPNGK--AVGSDFLWGSSLTYTCVEGYQL 3155

  Fly   992 ----------NR----------------------------------------------IGQYLRK 1000
                      ||                                              :|...|.
 Frog  3156 SLPAVLTCESNRSWVGELPQCFPVFCGDPGIPAHARRVDRGFSYRSSISFSCPPPLVLVGSVRRF 3220

  Fly  1001 CTEDGAWSGKQPRC-----ELATAEG------QETSELGTGVGIGATVI 1038
            |..||.|||.||.|     ...|..|      |.||:   |..:|:||:
 Frog  3221 CQSDGTWSGTQPSCIDPSHTTCTDPGIPSFGMQNTSQ---GFQVGSTVL 3266

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fwNP_511136.2 CCP 58..112 CDD:153056 12/34 (35%)
FTP 113..261 CDD:128870 35/208 (17%)
CLECT 281..403 CDD:153057 27/155 (17%)
PHA02927 <408..578 CDD:222943 63/243 (26%)
PHA02927 <508..696 CDD:222943 58/194 (30%)
PHA02639 643..>837 CDD:165022 59/203 (29%)
PHA02927 798..1014 CDD:222943 73/276 (26%)
csmd2XP_017947315.2 CUB 58..165 CDD:238001
CCP 171..229 CDD:153056
CUB 234..337 CDD:238001
CCP 375..433 CDD:153056
CUB 437..546 CDD:238001
CCP 553..607 CDD:153056
CUB 610..717 CDD:238001
CCP 723..781 CDD:153056
CUB 784..891 CDD:238001
CCP 899..953 CDD:153056
CUB 956..1064 CDD:238001
CCP 1071..1127 CDD:153056
CUB 1130..1237 CDD:238001
CCP 1243..1300 CDD:153056
CUB 1303..1411 CDD:238001
CCP 1417..1474 CDD:153056
CUB 1477..1582 CDD:395345
CCP 1590..1647 CDD:153056
CUB 1651..1758 CDD:238001
CCP 1767..1825 CDD:153056
CUB 1828..1933 CDD:238001
CCP 1941..1997 CDD:153056
CUB 2000..2107 CDD:238001
Sushi 2113..2168 CDD:459664 12/30 (40%)
CUB 2172..2277 CDD:238001 22/132 (17%)
CCP 2284..2342 CDD:153056 10/57 (18%)
CUB 2349..2455 CDD:238001 20/114 (18%)
PHA02927 <2478..2634 CDD:222943 28/165 (17%)
PHA02927 2645..2881 CDD:222943 73/244 (30%)
PHA02639 2822..>2999 CDD:165022 58/202 (29%)
Sushi 3004..3058 CDD:459664 17/54 (31%)
PHA02927 3058..3297 CDD:222943 51/215 (24%)
CCP 3301..3356 CDD:153056
Blue background indicates that the domain is not in the aligned region.

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