Protein Alignment HOXB6 and Abd-B

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_524896.2
• Gene: Abd-B / 47763
• FlyBaseID: FBgn0000015
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 93/331 - (28%)
• Similarity: 134/331 - (40%)
• Gaps: 92/331 - (27%)

Human     3 ETPPSPGSLPENAQVSRHSRRREPRSTGRQFCGFNAARRSDYKTQQIINPAEQQRPRAPPLPMSS 67
            :||..|.:..:....|.|.::...:.|..     :.|..:....||     :||:..|...|..:
  Fly   146 QTPTGPSAQQQQHLTSPHHQQLPQQQTPN-----SVASGASSNLQQ-----QQQQQNAAVAPGQT 200

Human    68 YFV----NSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPG---------------- 112
            ..|    .|..|.:::|.:|.....:.|      .|| |.|| ...|||
  Fly   201 QIVAPTTASVSPSSVSSQKEDINMSIQL------APL-HIPA-IRAGPGFETDTSAAVKRHTAHW 257

Human   113 --QDKGFATSSYYPPAGGGYGR----AAPCD---------YGPAPAFYREKESACALSGADEQPP 162
              .|:||  :.:|  ..|.|.|    |.|..         :||.   ||..::..|.:.|   ..
  Fly   258 AYNDEGF--NQHY--GSGYYDRKHMFAYPYPETQFPVGQYWGPN---YRPDQTTSAAAAA---AY 312

Human   163 FHPEPRKSDCAQDKSVFGETEEQKCSTPVYP---WMQRMNSCNSSSFGPSG-------------- 210
            .:...|....|..:||.| |.......|.|.   .::...|.|.||.|.||
  Fly   313 MNEAERHVSAAARQSVEG-TSTSSYEPPTYSSPGGLRGYPSENYSSSGASGGLSVGAVGPCTPNP 376

Human   211 -----------RRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMK 264
                       |:.|:.|:::|||||||||.:|.|:::::|.|:|..|.|||||:||||||||||
  Fly   377 GLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNLQLTERQVKIWFQNRRMK 441

Human   265 WKKESK 270
            .||.|:
  Fly   442 NKKNSQ 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	33/55 (60%)
Abd-B	NP_524896.2	Homeodomain	388..444	CDD:459649	33/55 (60%)