Protein Alignment HOXB6 and Dr

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 81/352 - (23%)
• Similarity: 125/352 - (35%)
• Gaps: 103/352 - (29%)

Human     4 TPPSP-----GSLPEN----AQVSRHSRRREPRSTGRQFCGFNAARRSDYKTQQIINPAEQQRPR 59
            |||.|     ..:|.|    |.|:.|:...:...........:.|..:..:.||     :|...|
  Fly   174 TPPPPPASAAAQVPANTFHPAAVAHHAHLLQAAHAAAAAHAQHQAMAAQLRQQQ-----QQADAR 233

Human    60 APPLPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYA--------------DPLRHYPAPYGPG 110
            |...|.|:....|:.|:..|.|.:..:...|..:..::              :.|:.:.|.:...
  Fly   234 ANSPPASTSSTPSSTPLGSALGSQGNVASTPAKNERHSPLGSHTDSELEYDEEMLQDHEADHDEE 298

Human   111 PG-----QDKGFATSSYYPPAG-GGYGRAAPCDYGPAPAFYREKE--SACALS------------ 155
            ..     :|.....|....|.| .|.|::....:||.|..:.:..  |..||:
  Fly   299 EDSIVDIEDMNADDSPRSTPDGLDGSGKSLESPHGPPPGSHMQSTILSPAALASGHVPIRPTPFS 363

Human   156 -------------------GADEQPPFHPEPRKSDCAQDKSVF------GETEEQKCSTPVYPWM 195
                               |..:.|||.|          ..:|      |:..|.       |.:
  Fly   364 ALAAAAVAWTGMGGGVPWPGTRQMPPFGP----------PGMFPGAGFGGDANEP-------PRI 411

Human   196 QRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQN 260
            :    ||.....|: |:.|..:|..|.|.|||:|...:||:...|.|.:.:|.|||.|:||||||
  Fly   412 K----CNLRKHKPN-RKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQN 471

Human   261 RRMKWKKESKLLSASQLSAEEEEEKQA 287
            ||.|.|:..:        ||.|:.|.|
  Fly   472 RRAKAKRLQE--------AEIEKIKMA 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	27/55 (49%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	27/55 (49%)