Protein Alignment HOXB6 and ro

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_524521.1
• Gene: ro / 43234
• FlyBaseID: FBgn0003267
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 80/268 - (29%)
• Similarity: 95/268 - (35%)
• Gaps: 61/268 - (22%)

Human    35 GFNAARRSDYKTQQIINPAEQQRPRAPPLPMSSYFVNSTFPVTLASGQESFLGQLPLYSS--GYA 97
            |....:||| ....|.|......|:.|..|...:              |...|.|...||  |..
  Fly    13 GSPGIKRSD-SLDPIANTTILSVPQRPSSPRQFF--------------ERLYGHLETRSSENGEI 62

Human    98 D--PLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQ 160
            |  ...|.|.|.......|.|..:|   |.......|.:...| ||..||          |..:.
  Fly    63 DVGTHAHKPPPCDTPYHSDGGSVSS---PDISISDERTSLAAY-PAYDFY----------GHAKD 113

Human   161 PPFHPEPRKSDCAQDKSVFGETEEQKCS--------------TPVYPWMQRMN-------SCNSS 204
            .|.||..:............:...||.|              .||.|......       |...|
  Fly   114 YPQHPSQQHQQHHHHHHHPPQLVHQKLSYVSPPPAIAAGGAANPVLPHAFPAGFPSDPHFSAGFS 178

Human   205 SFGPSGRR--GRQ-----TYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRR 262
            :|....||  |||     |::..|||.||.|||.|.|::|.||.|:|..|.|||.||||||||||
  Fly   179 AFLARRRRKEGRQRRQRTTFSTEQTLRLEVEFHRNEYISRSRRFELAETLRLTETQIKIWFQNRR 243

Human   263 MKWKKESK 270
            .|.|:..|
  Fly   244 AKDKRIEK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	36/62 (58%)
ro	NP_524521.1	Homeodomain	196..248	CDD:459649	31/51 (61%)