Protein Alignment HOXB6 and C15

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 58/233 - (24%)
• Similarity: 83/233 - (35%)
• Gaps: 70/233 - (30%)

Human    55 QQRPRAPPLPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFAT 119
            ||........:::...|||:                    |.|..|..||
  Fly   124 QQEDHDLAYKLATSIANSTY--------------------GSAAALYSYP--------------- 153

Human   120 SSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEE 184
             ..||.|.||:....|....|             |:.|  .||.|.........:|:
  Fly   154 -HLYPSAAGGHVLRVPPQRTP-------------LTWA--LPPLHHAALAHQAVKDR-------- 194

Human   185 QKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCL 249
               ....:|..:|:.....:...|..::.|.::||.|..||||.||..:||....|..:|..|.:
  Fly   195 ---LAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKM 256

Human   250 TERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQA 287
            |:.|:|.||||||.||::        |.:.|.|.|:||
  Fly   257 TDAQVKTWFQNRRTKWRR--------QTAEEREAERQA 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	26/55 (47%)
C15	NP_476873.2	COG5576	<196..315	CDD:227863	35/99 (35%)
		Homeodomain	218..274	CDD:459649	26/55 (47%)