Protein Alignment HOXB6 and lbe

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 76/338 - (22%)
• Similarity: 111/338 - (32%)
• Gaps: 107/338 - (31%)

Human     4 TPPSPGSLPENAQVSRHSRRREPRSTG-RQFCGFNAARRSDYKTQQIINPAEQQRPRAPP----- 62
            ||..|.::||    .:.::..:....| :.|...:....|:.:.::.::|.......|||
  Fly   108 TPSPPSAVPE----PQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRPI 168

Human    63 LPMSSYFVNSTFP----------VTLASGQ-----ESFLG------------------------- 87
            .|........|.|          :.|.|||     :..||
  Fly   169 APSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYH 233

Human    88 -QLPLYSSGYADPLRHY---PAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREK 148
             ||..:.:..|..|||.   ||......|..:....||      ...|....|  .|..|...||
  Fly   234 RQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSS------SSNGSTECC--SPRQAEKLEK 290

Human   149 ------ESACALSGADEQPP--------------FHPEPRKSDCAQDKS---VFGETEEQKCSTP 190
                  ........::|||.              |....:..|.:||||   :|....:.|
  Fly   291 LTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPK---- 351

Human   191 VYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIK 255
                              ..|:.|..:|.:|..||||.|.|.:||:...|.|||.:|.|:..|:.
  Fly   352 ------------------KKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVI 398

Human   256 IWFQNRRMKWKKE 268
            .||||||.|.|::
  Fly   399 TWFQNRRAKQKRD 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	26/55 (47%)
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	26/55 (47%)