Protein Alignment HOXB6 and abd-A

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_732176.1
• Gene: abd-A / 42037
• FlyBaseID: FBgn0000014
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 320
• Identity: 106/320 - (33%)
• Similarity: 138/320 - (43%)
• Gaps: 71/320 - (22%)

Human     4 TPPSPGSLPENAQVSRHSRRREPRSTGRQFCGFNAARRSDYKTQQIINPAEQQRPRAPPLPMSSY 68
            ||||.|    |:|....|....|.::|.     ::..||          .....|.:.....|:.
  Fly   189 TPPSAG----NSQAGDSSCSPSPSASGS-----SSLHRS----------LNDNSPGSASASASAS 234

Human    69 FVNSTFPVTLASGQESFLGQLPLYSSGYADP-------LRHYPAPYGPGPG-------QDKGFAT 119
            ..:|......|:...:        ||.:|.|       :.::|:.:|...|       :||  :.
  Fly   235 AASSVAAAAAAAAAAA--------SSSFAIPTSKMYPYVSNHPSSHGGLSGMAGFTGLEDK--SC 289

Human   120 SSYYPPAGGGYGRAAPCDYGPAPA------FYREKESACALSGADEQPPFHPEPRKSDCAQDKS- 177
            |.|.......|...:.    ||.|      ||:...:|.:...|........:...:.|.|..|
  Fly   290 SRYTDTVMNSYQSMSV----PASASAQFAQFYQHATAAASAVSAASAGAIGVDSLGNACTQPASG 350

Human   178 ----VFGETEEQKCSTPVYPWMQRMNSCNSSSF---------GPSG---RRGRQTYTRYQTLELE 226
                ..|.........|.|||| .:.....|.|         ||:|   |||||||||:||||||
  Fly   351 VMPGAGGAGGAGIADLPRYPWM-TLTDWMGSPFERVVCGDFNGPNGCPRRRGRQTYTRFQTLELE 414

Human   227 KEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQ 286
            ||||:|.|||||||||||||||||||||||||||||||.|||.:.:......|..:.|:|
  Fly   415 KEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARRDREEQ 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	51/55 (93%)
abd-A	NP_732176.1	Homeodomain	399..455	CDD:459649	51/55 (93%)
		Abdominal-A	456..478	CDD:403567	4/19 (21%)