Protein Alignment HOXB6 and ems

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 83/329 - (25%)
• Similarity: 117/329 - (35%)
• Gaps: 94/329 - (28%)

Human     2 RETPPSPGSLPENAQVSRHSRRREPRSTGRQFCGFNAARRSDYKTQQI----INPAEQQRPRAPP 62
            ||..|:|   |...|....::|.:|..|..:.....:::.|...|..|    ..|.:||:.:.||
  Fly   179 RERSPAP---PAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPP 240

Human    63 LPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPG----PGQDKGFATSSYY 123
                    |...|..:..|     |..|:...|........|.|.|||    |....|.......
  Fly   241 --------NYPKPAMMHPG-----GAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKAL 292

Human   124 PP-----------------AGGGYGRAAPCD----YGPAPAFYREKESACALSGADEQPP----F 163
            ||                 |...:..||...    .|||.|       |.|.:|.   ||    |
  Fly   293 PPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAA-------AAAAAGL---PPHAAQF 347

Human   164 HPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNS------CNSSSFGPSGRRGRQTYTRY-- 220
            .|.|   ..|:|            |..:|||:...:.      ...|...|..|:.::..|.:
  Fly   348 MPNP---GMARD------------SYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSP 397

Human   221 -QTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEE 284
             |.|:||..|..|:|:....|..:|..|.|:|.|:|:||||||.|.|:           .::|:|
  Fly   398 SQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR-----------MQQEDE 451

Human   285 KQAE 288
            |..|
  Fly   452 KGGE 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	23/58 (40%)
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	22/55 (40%)