DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HOXB6 and Scr

DIOPT Version :9

Sequence 1:	XP_011523029.1	Gene:	HOXB6 / 3216	HGNCID:	5117	Length:	288	Species:	Homo sapiens
Sequence 2:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	157	Identity:	79/157 - (50%)
Similarity:	96/157 - (61%)	Gaps:	17/157 - (10%)

- Green bases have known domain annotations that are detailed below.

Human   127 GGGYGRAAPCDYGPAPAFYREKESACALSG--ADEQPPFH-PEPRKSDCAQDK-SVFGETEE--- 184
            ||....||      |.|......|...:||  .:...|.| |....||...|. :..|.::.
  Fly   238 GGSLAAAA------AAAGLNNNHSGSGVSGGPGNVNVPMHSPGGGDSDSESDSGNEAGSSQNSGN 296

Human   185 -QKCSTPVYPWMQRMNSCNSSSFGPSG--RRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHA 246
             :|....:||||:|:: ..:|:...:|  :|.|.:||||||||||||||:|||||||||||||||
  Fly   297 GKKNPPQIYPWMKRVH-LGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 360

Human   247 LCLTERQIKIWFQNRRMKWKKESKLLS 273
            ||||||||||||||||||||||.|:.|
  Fly   361 LCLTERQIKIWFQNRRMKWKKEHKMAS 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeobox	214..266	CDD:278475	48/51 (94%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	49/52 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.810