Protein Alignment HOXB6 and pb

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 253
• Identity: 78/253 - (30%)
• Similarity: 102/253 - (40%)
• Gaps: 79/253 - (31%)

Human    61 PPLPMSSYFVNSTFP------------VTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQ 113
            ||:| |...||...|            :|.:.|  .|:...|    ..|:.|.|. :|..|..|.
  Fly    67 PPVP-SVLMVNKMTPNCDKRSADTAYWMTASEG--GFINSQP----SMAEFLNHL-SPESPKIGT 123

Human   114 DKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSV 178
            ..|..       |.||.|.....:.|....:                              ...|
  Fly   124 PVGSG-------AIGGVGVNVNVNVGVGVGY------------------------------PVGV 151

Human   179 FGETEEQKCSTPVYPWMQRMNSCNSSS------------FGPSG---RRGRQTYTRYQTLELEKE 228
            ..:|.:...|.|.||||:...:...||            |.|..   ||.|..||..|.||||||
  Fly   152 VPQTPDGMDSVPEYPWMKEKKTSRKSSNNNNQGDNSITEFVPENGLPRRLRTAYTNTQLLELEKE 216

Human   229 FHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQ 286
            ||:|:||.|.||||||.:|.|||||:|:||||||||.|:::       ||..::|:.:
  Fly   217 FHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQT-------LSKTDDEDNK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	39/55 (71%)
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	39/55 (71%)