Protein Alignment HOXB6 and inv

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_523699.3
• Gene: inv / 36239
• FlyBaseID: FBgn0001269
• Length: 576
• Species: Drosophila melanogaster
• Alignment Length: 204
• Identity: 65/204 - (31%)
• Similarity: 83/204 - (40%)
• Gaps: 49/204 - (24%)

Human   118 ATSSYYPPAGGGYGRAAPCDY--GPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQ--DKSV 178
            ||||......|     ||.|.  .|.||.......|...||.|...|. ..|....|.:  |:..
  Fly   372 ATSSSTTNTSG-----APVDLVKSPPPAAGAGATGASGKSGEDSGTPI-VWPAWVYCTRYSDRPS 430

Human   179 FGETEEQKCSTPVYPWMQRMNSCNSSSFG-----------------PSGRRGRQTYTRYQTLELE 226
            .|.:  .:...|..|      :.:||:.|                 |..:|.|..::..|...|:
  Fly   431 SGRS--PRARKPKKP------ATSSSAAGGGGGGVEKGEAADGGGVPEDKRPRTAFSGTQLARLK 487

Human   227 KEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKES--KLLSASQLSAE--------- 280
            .||:.|||||.:||.:::..|.|.|.||||||||:|.|.||.|  |...|.||.|:
  Fly   488 HEFNENRYLTEKRRQQLSGELGLNEAQIKIWFQNKRAKLKKSSGTKNPLALQLMAQGLYNHSTIP 552

Human   281 ---EEEEKQ 286
               ||||.|
  Fly   553 LTREEEELQ 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	26/55 (47%)
inv	NP_523699.3	Homeodomain	472..528	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	529..554	CDD:431338	6/24 (25%)