Protein Alignment HOXB6 and unpg

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_477146.1
• Gene: unpg / 35942
• FlyBaseID: FBgn0015561
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 86/352 - (24%)
• Similarity: 127/352 - (36%)
• Gaps: 109/352 - (30%)

Human     4 TPPSPGSLPENAQVSRHSRRREPRSTG----------RQFCGFNA------ARRSDYKTQQII-- 50
            |||||   ||.....:.:.:.:..|..          .||..:|.      |:..:..|..|.
  Fly    46 TPPSP---PEERDQEQEAEQEQELSARAMVASSALGLTQFPLYNPWLHGYFAQNHERLTHLIAGG 107

Human    51 ---------NPAEQQ-----RPRAPPLPMSSYFVNSTFPVTL--------------ASG------ 81
                     :||.||     :|:.||....::.:....|.||              |:|
  Fly   108 CYLPSSPAGHPAAQQPQAQAQPQPPPPHPPTHALEKQLPPTLPHPLDTRFLPFNPAAAGVAPTDL 172

Human    82 ---------QESFLGQLPLYSSGYADPLRHYPAP---------------YGPGPGQDKGFATSSY 122
                     .:.::..|.:::.     |:|..|.               ..|.|.|    |.||
  Fly   173 SYRRLAELMNQDYVHSLSVHAR-----LQHMAAAGRMHEDQANPGMAQLQEPTPPQ----AHSS- 227

Human   123 YPPAGGGYGRAAPC-DYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKS---VFGETE 183
             |...|.:....|. |.|....|....:|...:|       ....||..:...|||   .:..::
  Fly   228 -PAKSGSHSPMEPALDVGMDEDFECSGDSCSDIS-------LTMSPRNYNGEMDKSRNGAYTNSD 284

Human   184 EQKCSTPVYPWMQ--------RMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRR 240
            .:.||.......:        :.:..|.||.....||.|..:|..|.||||:|||..:||:...|
  Fly   285 SEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYLSLTER 349

Human   241 IEIAHALCLTERQIKIWFQNRRMKWKK 267
            .:||.:|.|:|.|:||||||||.|||:
  Fly   350 SQIATSLKLSEVQVKIWFQNRRAKWKR 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	31/55 (56%)
unpg	NP_477146.1	Homeodomain	324..376	CDD:459649	28/51 (55%)