Protein Alignment HOXB6 and cad

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 68/264 - (25%)
• Similarity: 102/264 - (38%)
• Gaps: 72/264 - (27%)

Human    79 ASGQESFLGQLPLYSSGYADPLRHYPA------------PYGPGPGQDKGFATSSY--YPPAGGG 129
            :|..::|:..:|..:........|:.|            ..|..||..:...|:|.  ...||||
  Fly    88 SSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGG 152

Human   130 YGRAAPCDYGP--APAFYRE------KESACALSGADEQPPFHPEPRKS---------------- 170
            .|.....|.||  ||..:::      ......:||::...|..|....|
  Fly   153 GGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNN 217

Human   171 --------------DCAQDKSVFGETEEQKCSTPVYPWMQR-----------MNSCN----SSSF 206
                          :...:.||...........|.:.||::           .:|.|    |...
  Fly   218 NNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLL 282

Human   207 GPSGR-----RGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWK 266
            ..||:     :.|..||.:|.||||||:..:||:|.||:.|:|..|.|:|||:||||||||.|.:
  Fly   283 DASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKER 347

Human   267 KESK 270
            |::|
  Fly   348 KQNK 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	31/60 (52%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	31/54 (57%)