Protein Alignment HOXB6 and bsh

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Alignment Length: 277
• Identity: 76/277 - (27%)
• Similarity: 95/277 - (34%)
• Gaps: 96/277 - (34%)

Human     1 MRETPPSPGSLPENAQVSRHSRRREPRSTGRQF---CGFNAARRSDYKTQQIINPAEQQRPRAPP 62
            |..||.|          :.|||.......|.|.   .|..||:.....|.|         |:.||
  Fly   143 MHSTPRS----------NHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQ---------PQPPP 188

Human    63 LPMSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYP-APYGPGPGQDKGF--ATSSYYP 124
            .|          |:...||.          |:|..     || |||     .|.||  .|..|..
  Fly   189 PP----------PLNGGSGA----------SNGVL-----YPNAPY-----TDHGFLQMTLGYLS 223

Human   125 PAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSV---FGETEEQK 186
            |:.|.|....|.....|..|          .||    ||...|   .|..:.::   .|....:.
  Fly   224 PSSGTYKSVDPYFLSQASLF----------GGA----PFFGAP---GCVPELALGLGMGVNALRH 271

Human   187 CSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTE 251
            |..                     |:.|..::..|...|||.|...|||:...|:|:|.||.|:|
  Fly   272 CRR---------------------RKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSE 315

Human   252 RQIKIWFQNRRMKWKKE 268
            .|:|.||||||||.||:
  Fly   316 TQVKTWFQNRRMKHKKQ 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	27/55 (49%)
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	27/55 (49%)