Protein Alignment HOXB6 and H2.0

DIOPT Version :10

• Sequence 1: XP_011523029.1
• Gene: HOXB6 / 3216
• HGNCID: 5117
• Length: 288
• Species: Homo sapiens
• Sequence 2: NP_523488.2
• Gene: H2.0 / 33841
• FlyBaseID: FBgn0001170
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 64/265 - (24%)
• Similarity: 98/265 - (36%)
• Gaps: 66/265 - (24%)

Human    66 SSYFVNSTFPVTL---ASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAG 127
            |..|.::|.|.|.   :|....|:|...|:...|.|    |.:...|.|.:....|..:|...|.
  Fly   122 SRRFGHATLPPTFTPTSSHTYPFVGLDKLFPGPYMD----YKSVLRPTPIRAAEHAAPTYPTLAT 182

Human   128 GGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFH------PEPRKSDCA------------- 173
            ....|           |::.::.........:..|.|      |.|..|..|
  Fly   183 NALLR-----------FHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSL 236

Human   174 ----QDKSVFGETEEQKCS-TPVYPWMQRM-------------NSCNSSSFGPSGRR----GRQT 216
                |.:...|:|.:|... .|..|.....             |...::|.|.:|:|    .|..
  Fly   237 QLTQQQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRAV 301

Human   217 YTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEE 281
            ::..|...||.:|...:|:|:..|.::|..|.||:.|:|:|||||||||:...:.|.:.|
  Fly   302 FSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQ----- 361

Human   282 EEEKQ 286
              |||
  Fly   362 --EKQ 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB6	XP_011523029.1	Homeodomain	211..267	CDD:459649	24/59 (41%)
H2.0	NP_523488.2	Homeodomain	292..352	CDD:459649	24/59 (41%)