DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gd and svh-1

DIOPT Version :9

Sequence 1:	NP_001259479.1	Gene:	gd / 32159	FlyBaseID:	FBgn0000808	Length:	531	Species:	Drosophila melanogaster
Sequence 2:	NP_501379.2	Gene:	svh-1 / 182375	WormBaseID:	WBGene00006620	Length:	951	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	75/303 - (24%)
Similarity:	131/303 - (43%)	Gaps:	60/303 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 QFVDESEAEAIESDSA------DSLPSITRGSWPWLAAIYVNNLTSLDFQCGGSLVSARVVISSA 294
            ::|:.:..:|.:|..|      :::|    |::||.||:  .|..:....||.|::....:|::|
Worm   696 RYVEVNARDAAKSRIARVVGGFETVP----GAFPWTAAL--RNKATKAHHCGASILDKTHLITAA 754

  Fly   295 HCFKLFNKRYTSNEVLVFLGRHNLKNWNEEGSLAAPVDGIYIHPDFNSQLSSYDADIAVI-ILKD 358
            |||: .::|.:|.||:|....:|..:.||:   ...:..|:.:|.:....|.   |||:: |...
Worm   755 HCFE-EDERVSSYEVVVGDWDNNQTDGNEQ---IFYLQRIHFYPLYKDIFSH---DIAILEIPYP 812

  Fly   359 EVRFNTFIRPACLWSGSSKTEYIVGERGIVIGWSFDRTNRTRDQKLSSELPGKKSTDASAPKVVK 423
            .:.||.:.:|.||  .|....|..|.:.:|.||.  .......::|.:.|
Worm   813 GIEFNEYAQPICL--PSKDFVYTPGRQCVVSGWG--SMGLRYAERLQAAL--------------- 858

  Fly   424 APIVGNAECFRANAHFRSLSSNRTFCAGIQAEERDTHQSGASIYTGISGAGLFIRR-NNRWMLRG 487
            .||:...:|..::..:.|:|.: .||||..       :.|.....|.||.....|| :..::|.|
Worm   859 IPIINRFDCVNSSQIYSSMSRS-AFCAGYL-------EGGIDSCQGDSGGPFACRREDGAFVLAG 915

  Fly   488 TVSAALPAVETPDAESSHKLCCKNQYIIYADVAKFLDWITAFV 530
            .:|......:            |.|..||..||.:|.||:|.:
Worm   916 VISWGDGCAQ------------KKQPGIYTMVAPYLSWISAII 946

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gd	NP_001259479.1	GD_N	27..124	CDD:292649
		Tryp_SPc	257..526	CDD:238113	67/270 (25%)
		Tryp_SPc	258..526	CDD:214473	67/269 (25%)
svh-1	NP_501379.2	KR	227..306	CDD:214527
		LDLa	320..355	CDD:238060
		PAN_AP_HGF	373..434	CDD:238532
		LDLa	558..590	CDD:197566
		SRCR_2	599..681	CDD:382996
		Tryp_SPc	713..945	CDD:238113	70/283 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24258
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100