Protein Alignment cac and pias2

DIOPT Version :9

• Sequence 1: NP_001356945.1
• Gene: cac / 32158
• FlyBaseID: FBgn0263111
• Length: 2110
• Species: Drosophila melanogaster
• Sequence 2: XP_031757544.1
• Gene: pias2 / 779910
• XenbaseID: XB-GENE-988474
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 104/574 - (18%)
• Similarity: 179/574 - (31%)
• Gaps: 166/574 - (28%)

  Fly  1626 RTQLPYPTYGTTSLCQRSRSPSPARLQEMRERDRLGYGIDMGVTHVQHSYPTLASRRAGIGRRLP 1690
            |.:.|....|.|.|       :|.|..............|:.|:.: ||.|:.:..        |
 Frog    62 RRRFPRTLDGVTGL-------APIRSNVFNLDSSAPVDPDLAVSGM-HSLPSTSVS--------P 110

  Fly  1691 PTPSKP-STLQLKPTNINFPKLNASPT-HTHHSTPHSVHSLPHH--RDLLRDPRDMYYSSRERER 1751
            .:|:.| .::.|:.|...|.....||: ...|...| :.|||.:  .|:|..|..:..::.:|.:
 Frog   111 CSPASPLGSVLLQDTKAPFEIQQLSPSIPPVHPDVH-LKSLPFYDVLDVLIKPTSLVQNTLQRFQ 174

  Fly  1752 DR--------ERLRDRDRDRD------RDRLHEYDLRYEYRDRERELYERERDREREVERERLEY 1802
            ::        :::|:....||      ||    |.::.:.|....|....:.|
 Frog   175 EKFFIFALTPQQVREVVISRDYMPGGRRD----YSVQVQLRLCLAETSCPQED------------ 223

  Fly  1803 IAPLSFEQALAMGRTGRVLPSPVLNGFKPKSGLNPRHSDSDEEDWCXQRLXLRSRNRKDQIWVXH 1867
                ::..:|.:...|::.|.|.. ...||:|:..:............||.....|:....|...
 Frog   224 ----NYPSSLCIKVNGKLFPLPGC-AVPPKNGVEQKRPGRPLNITSLVRLSSAVPNQVSISWASE 283

  Fly  1868 QAICSSLSA--------------------PNLDHN-----------------FDTIRHSYQIPEH 1895
            .....|:|.                    .|.||:                 ..::|.|...|..
 Frog   284 IGKNYSMSVYLVRQLTSAVLLQKLKMKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLMCPLG 348

  Fly  1896 LQNLPYLCPPVHQHQHQHQTQTQNQRQHQDQHLYQRYGTNVSTPKLGTTISDIK-------LAGV 1953
            ...|...|..|          |.:..|..|..||.:  .|...|.....:.|.|       :.|:
 Frog   349 KMRLTIPCRAV----------TCSHLQCFDAALYLQ--MNEKKPTWICPVCDKKASYESLIIDGL 401

  Fly  1954 SLQELSPNRQPQSQQKQEQQLHQDG-WLRWYRQSGPYGSPVMASLPETRATSPH----------- 2006
            .::.|:     |.....|.:..||| |.....:..|..||        ....||
 Frog   402 FMEILN-----QCSDVDEIKFQQDGSWCPMRPKKEPMTSP--------STQYPHIEGAGVISKIC 453

  Fly  2007 SDIEFIRTMKRSETGTTAITPRTTKTE----AMILSVPITITSPLAIKKI--YSDNDINYNTERG 2065
            |.:|...|.::::.....:|..::..:    |....|.:|.:...|:|.:  |..:.|......|
 Frog   454 SAVEGGETTRKNKAEVIDLTLESSSDDDEPPAKKECVYLTESQEAAMKGVLSYQPSSIRVGKVAG 518

  Fly  2066 TDNDRVDDAPAH--------HYHQPELTTPDLQDEPP--------LQQHHQHYP 2103
                 ::..|.|        |:|.|.:.  .:..|.|        .....|:||
 Frog   519 -----IESEPMHPSMAGYADHFHHPAIA--GISAELPGLDFLSLVSMDPQQYYP 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124
		Ion_trans	441..677	CDD:334124
		Ion_trans	769..1050	CDD:334124
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
pias2	XP_031757544.1	SAP	11..45	CDD:128789
		PINIT	146..295	CDD:405075	30/170 (18%)
		SP-RING_PIAS	342..389	CDD:319704	12/58 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860