DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cac and bicdl1

DIOPT Version :9

Sequence 1:	NP_001356945.1	Gene:	cac / 32158	FlyBaseID:	FBgn0263111	Length:	2110	Species:	Drosophila melanogaster
Sequence 2:	XP_031757461.1	Gene:	bicdl1 / 779781	XenbaseID:	XB-GENE-5811431	Length:	603	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	77/420 - (18%)
Similarity:	141/420 - (33%)	Gaps:	135/420 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1736 LRDPRDMYYSSRERERD-------RERLRDRDRDRDR----------DRL-------HEYDLRYE 1776
            :|:..::....|::|:|       .:.|.:|::|..|          |:|       ||...:.|
Frog    56 VREQSELLCIIRQKEKDLVLAARLGKALLERNQDMSRRYEEMQREMTDKLEHLEQEKHELKRKLE 120

  Fly  1777 YRDRERE-----------LYERERDRE----REVERERLEYIAPLS------FEQALAMGRTGRV 1820
            .|:.|.|           |.:.|.:::    ||.:||:|..:..||      .||........|.
Frog   121 NREGEWEGRVSELESDVKLLQEELEKQQVNLREADREKLSVVQELSEQNQRLLEQLSRATEMERQ 185

  Fly  1821 LPSPV---LNGFKPKSGLNPRHSDSDEEDWCXQRLXLRS-RNRKDQIWVXHQAICSSLSAPNLDH 1881
            |...|   ...|:.||....:|....|.... |.| ::. .:||.:                |:.
Frog   186 LSQQVNVLQEEFREKSLSTSQHVSRLESLLAEQILEIKMLSDRKRE----------------LEQ 234

  Fly  1882 NFDTIRHSYQIPEHLQNLPYLCPPVHQHQHQHQTQTQNQRQHQDQHLYQRYGTNVSTPKLGTTIS 1946
            ...||...   .|.||.|      |.:.|.:..:..|           |.:|.::...:....|.
Frog   235 QLSTIMEE---NEQLQGL------VEELQDKELSLNQ-----------QNFGKDLQLRESQLEIE 279

  Fly  1947 DIKLAGVSLQ------------------------ELSPNRQPQSQQKQEQQLHQDGW-------- 1979
            :::|:...|:                        |:..:.:.:.|:::.:||....|
Frog   280 EMRLSYRQLEGKLEELREEKSLQHMNSTSTSLLSEIEQSIEAEEQEQEREQLRLQLWEAHCQVRS 344

  Fly  1980 ----LRWYRQSGPYGSPVMASLPETRATSPHSDIEFIRTMKRSETGTTAITPRTTKTEAMILSVP 2040
                ||. .:|........:|:.|:..||...|:             .|.:.||..:|...|.:.
Frog   345 LCCQLRG-NESADSAVSTDSSMDESSETSSAKDV-------------PAGSLRTALSELKSLILS 395

  Fly  2041 ITITSPLAIKKIYSDNDINYNTERGTDNDR 2070
            |..|...|..:...|:.:....::.:::.|
Frog   396 ILETCDSASSRKCEDDGLEEQIKQTSEDSR 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124
		Ion_trans	441..677	CDD:334124
		Ion_trans	769..1050	CDD:334124
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
bicdl1	XP_031757461.1	SbcC	<49..>533	CDD:223496	77/420 (18%)
bicdl1	XP_031757461.1	SMC_prok_A	<81..>300	CDD:274009	50/254 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900