Protein Alignment cac and tpcn1

DIOPT Version :9

• Sequence 1: NP_001356945.1
• Gene: cac / 32158
• FlyBaseID: FBgn0263111
• Length: 2110
• Species: Drosophila melanogaster
• Sequence 2: XP_695923.4
• Gene: tpcn1 / 567534
• ZFINID: ZDB-GENE-060526-199
• Length: 811
• Species: Danio rerio
• Alignment Length: 632
• Identity: 141/632 - (22%)
• Similarity: 254/632 - (40%)
• Gaps: 114/632 - (18%)

  Fly   477 EFIFLGLFMSEMFIKMYALGPRIYFESSFNRFDCVVISGSIFEVIWSEVKGGSFGLSVLRALRLL 541
            |.:.|.:...|:.:|:..||...:...........|:.....|.|...|:..|. |.|.||||
Zfish   141 ELLALVMVAFELCMKLRWLGFHTFIRHKRTMVKTSVLFIQFIEAIVVLVRQTSH-LRVTRALR-- 202

  Fly   542 RIFKV-TKYWSSLRNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETNFN 605
            .||.| .:|..::|..:..:..|:...|.:|.||..|::|||:||..||.      ..|.:..|:
Zfish   203 PIFLVDCRYCGAVRRNLRQIFQSLPPFIDILLLLLFFMVIFAILGFCLFS------ANTADHYFS 261

  Fly   606 TFPIALLTVFQILTGEDWNEVMYQGIISQGGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNL 670
            |...:::::|.:||..::.:||....      .|.....|:|||.:....|.::|:.||:..|..
Zfish   262 TLENSIVSLFVLLTTANFPDVMMPAY------SKNRWSCIFFIVYLSIELYFIMNLLLAVVFDTF 320

  Fly   671 ANAQELTAAEEEQVEEDKEKQL-----QELEKEMEAL----QADGVHVENGDGAVA---PSKSKG 723
                       ..||:.|.|.|     ..:|...:.|    :.|||.::..||.:.   |..:
Zfish   321 -----------NGVEKMKFKSLLLHKRSAIEHAFQLLVSRQRPDGVSLKQFDGLMRFYHPRMT-- 372

  Fly   724 KKKEEEKKEEEEVTEGPKPMLPYSSMF----ILSPTNPIRR-GAHWVVNLP-------------- 769
              ..:.....:.:.....|||.....:    ::......|| |.||..:||
Zfish   373 --PRDRFLTFKALNHSGAPMLSLQDFYKFYEVIGLKWKARRSGEHWFDDLPRTALLIFKGINLLV 435

  Fly   770 ---YFDFFIMVVISMSSIALAAE-DPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHP 830
               .|.:.:.:|::::.|.:..| :.:.:.....:::.:....|..::.||:||||..||    |
Zfish   436 KSKAFQYAMYLVVAVNGIWILVETNMLNDGISWTRVVPWSYIIFLTIYGIEVLLKITGLG----P 496

  Fly   831 GSYLREFWNIMDAVVVICA---AVSFGFDMSGSSAGQNLSTIKSLRVLRVLRPLKTIKRVPKLKA 892
            .:|....||:.|..|.:.|   .::..|||         .....:.|||.|:.|:..|...:.:.
Zfish   497 ITYFSSGWNLFDFSVTVFAFLGLIALAFDM---------EPFYFIVVLRPLQLLRLFKIKQRYRN 552

  Fly   893 VFDCVVNSLKNVVNILIVYILFQFIFSVIGVQLFNGKFF-YCTDESKHTSAECQGSYFKYEEDEL 956
            |.|.:......:.::.:..|:|.:.|:::|::.|....: .|.|.|...::..|.:.......||
Zfish   553 VLDTMFELFPRMASLGLTLIIFYYSFAIVGMEFFADVIYPNCCDNSTVAASYRQINVTTGNRTEL 617

  Fly   957 LPKQELRVWKPRAFHY----DNVAAAMLTLFAVQTGEGWPQVLQHSMAATYEDRGPIQNFRIEMS 1017
               ||       .::|    :|:.::.:|||.:.....|...::...:.|      ....|:...
Zfish   618 ---QE-------GYYYLNNFNNILSSFVTLFELTVVNNWYITMEGVTSQT------THWSRLYFM 666

  Fly  1018 IFYIVYFIVFPFFFVNIFVALII------ITFQEQGEAELQDGEIDK 1058
            .||||..:|     :.|.||.|:      :.:..:....|.|.|.:|
Zfish   667 TFYIVTMVV-----MTIIVAFILDAFVFRMNYSRKNREPLDDPEDEK 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124
		Ion_trans	441..677	CDD:334124	53/200 (27%)
		Ion_trans	769..1050	CDD:334124	62/312 (20%)
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
tpcn1	XP_695923.4	Ion_trans	139..325	CDD:278921	54/209 (26%)
		Ion_trans	477..688	CDD:278921	57/244 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810