Protein Alignment cac and CATSPER2

DIOPT Version :9

• Sequence 1: NP_001356945.1
• Gene: cac / 32158
• FlyBaseID: FBgn0263111
• Length: 2110
• Species: Drosophila melanogaster
• Sequence 2: NP_001269239.1
• Gene: CATSPER2 / 117155
• HGNCID: 18810
• Length: 534
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 90/328 - (27%)
• Similarity: 162/328 - (49%)
• Gaps: 40/328 - (12%)

  Fly   433 WIRHTVKTQWFYWFVIVLVFLNTVCVAVEHYGQPSFLTEF------LYYAEFIFLGLFMSEMFIK 491
            |....::...|..|:|.||||||:.:.||.....|..|:.      |..|.:..|.:|:.|:.:|
Human   106 WAGWVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK 170

  Fly   492 MYALGPRIYFESSFNRFDCVVISGSIFE--VIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSLR 554
             :.....::::|::|.||.||...|:..  |:...|.|.|..|.:||..|:||..|:...:..::
Human   171 -WLSNFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQ 234

  Fly   555 NLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGGQFNLPGGTPETN--FNTFPIALLTVFQI 617
            .:::.|:.:::|:..||.||.:|..|||:.|:.:|......|....|.:  |:..|.:|:|||.:
Human   235 IIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVFSEYTRSPRQDLEYHVFFSDLPNSLVTVFIL 299

  Fly   618 LTGEDWNEVMYQGI-----ISQGGAQKGMIYSIYFIVLVLFGNYTLLNVFLAIAVDNLANAQ--- 674
            .|.:.|..:: |.:     :|:      :..|||||:.:|.|:....::.:|:.|.|..|.:
Human   300 FTLDHWYALL-QDVWKVPEVSR------IFSSIYFILWLLLGSIIFRSIIVAMMVTNFQNIRKEL 357

  Fly   675 -ELTAAEEEQVEEDK-EKQLQELEKEM--EALQADGVHVENGDGAVAPSKSKGKKKEEEKKEEEE 735
             |..|..|.|::.|. ::|:.:..|.|  |||.:....:|:          :|..::.|..:..|
Human   358 NEEMARREVQLKADMFKRQIIQRRKNMSHEALTSSHSKIED----------RGASQQRESLDLSE 412

  Fly   736 VTE 738
            |:|
Human   413 VSE 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124
		Ion_trans	441..677	CDD:334124	73/254 (29%)
		Ion_trans	769..1050	CDD:334124
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
CATSPER2	NP_001269239.1	Ion_trans	178..356	CDD:278921	53/184 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900