Protein Alignment cac and tpcn1

DIOPT Version :9

• Sequence 1: NP_001356945.1
• Gene: cac / 32158
• FlyBaseID: FBgn0263111
• Length: 2110
• Species: Drosophila melanogaster
• Sequence 2: XP_012825344.2
• Gene: tpcn1 / 100497529
• XenbaseID: XB-GENE-984919
• Length: 798
• Species: Xenopus tropicalis
• Alignment Length: 786
• Identity: 160/786 - (20%)
• Similarity: 316/786 - (40%)
• Gaps: 222/786 - (28%)

  Fly    86 VEASLKILALGLVL-----------------HKHSYLRNIWNIMDFFVVVTGFMTQYPQIGPEVD 133
            |.|:|::|||.||:                 |:.:.|::...::.|...:...:.|...:
 Frog   131 VHATLELLALALVVFELAMKMRWLGGKTFLRHRRTMLKSAVLVVQFIEAIVVLVRQTSHV----- 190

  Fly   134 LRTLRAIRVLRPLKLVS----GIPSLQVVLKSIIKAMAPLLQIGLLVLFAIVIFAIIGLEFYSGA 194
                |..|.|||:.||.    |  :::..|:.|.:::.|.:.|.||:||.:|||||:|...:|
 Frog   191 ----RVTRALRPIFLVDCRYCG--AVRRNLRQIFQSLPPFIDILLLLLFFMVIFAILGFYLFS-- 247

  Fly   195 LHKTCYSLEDPNKLVKEGESETPCNTDNILEKATGSFVCNNTTSMCLEKWEGPNSGITSFDNIGF 259
                    .|||.                                            ..|..:..
 Frog   248 --------SDPND--------------------------------------------PYFSTLEN 260

  Fly   260 AMLTVFQCITMEGWTAILYWTNDALGSAFN---W--IYFVPLIVIGSFFMLNLVLGVLSGEFAK- 318
            :::::|..:|...:.       |.:..|::   |  |:|:..:.|..:|::||:|.|:...|..
 Frog   261 SLVSLFVLLTTANFP-------DVMMPAYSRNPWSCIFFIIYLSIELYFIMNLLLAVVFDTFNDI 318

  Fly   319 EREKVENRQEFLKLRRQQQLERELNGYVEWICKAEEVILAEERTTEEEKMH---IMEARRRNAAK 380
            |::|.::    |.|.::..::.           :.:::.:.:.|:.....|   :|:..:.:.:.
 Frog   319 EKKKFKS----LLLHKRSAIQH-----------SYQLLHSTQGTSGVSFRHFNGMMKFYKPSMSA 368

  Fly   381 RKKLKSLGKSKSTDTEEEEAEEDYGDDGYLKTRSKPQGSCTGFWRAEKRFRFW------------ 433
            |.:..:....|.:..|....::.|.....::.:          |:.:|....|
 Frog   369 RDRYLTYRALKQSQAENLRLKDFYHFYEVVELK----------WKVQKIREHWFDDLPPTALLIF 423

  Fly   434 --IRHTVKTQWFYWFVIVLVFLNTVCVAVEHY----GQPSFLTEFLYYAEFIFLGLFMSEMFIKM 492
              :.....::.|.:.:..:|.:|...:..|.:    |  ::..|.:.::..:||.::.||:.:|:
 Frog   424 KGVNVLANSRVFQYIMYAVVAINGFWILAETFMLQGG--NYFPEGVPWSYIVFLTIYGSELLLKL 486

  Fly   493 YALGPRIYFESSFNRFDCVV----ISGSIFEVIWSEVKGGSFGLSVLRALRLLRIFKVTKYWSSL 553
            ..|||..||.|.:|.|||.|    :.|.:  |:...:|...| :.|||.|:|||:||:.|.:.::
 Frog   487 TGLGPVEYFTSGWNFFDCSVTLLALLGLL--VLAFNMKPFYF-IVVLRPLQLLRLFKMKKRYRTV 548

  Fly   554 RNLVISLLNSMRSIISLLFLLFLFILIFALLGMQLFGG--------------------------- 591
            .:.:..||..|.| :.|..|:|.:  .|:::||:.|.|
 Frog   549 LDTMFELLPRMAS-LGLTLLIFYY--SFSIVGMEFFSGVLYPNCCNTSTVADSYRWLNRTVGNQT 610

  Fly   592 QFNLPGGTPETNFNTFPIALLTVFQILTGEDWNEVMYQGIISQGGAQKGMIYSIYFIVLVLFGNY 656
            ||. .|.....|||....:.:|:|::....:|..:| :|:.||......:.:.:::||.::
 Frog   611 QFE-EGYYYLNNFNNILNSFVTLFELTVVNNWYIIM-EGVTSQTSHWARLYFMVFYIVTMV---- 669

  Fly   657 TLLNVFLAIAVDN----LANAQELTAAEEE-----QVEEDKEK--------QLQELEKEMEALQA 704
             :|.:.:|..:|:    :...::...||:|     ::|..||:        |..:...:|..|.:
 Frog   670 -VLTIIVACILDSFVFRMNYCRKNRDAEDEKGITLEMEVGKEELTLILRHTQSSDERSQMRKLLS 733

  Fly   705 DGVHVENGDGAVAPS------KSKGKKKEEEKKEEEEVTEGPK--PMLPYSSMFILSPTNPIRRG 761
               |:::.:   :||      :|:.|.....|..|||:.|..|  ..|.......|.||:...|.
 Frog   734 ---HLQSNE---SPSILFLGRRSRTKSDLSRKMYEEEIQEWYKEHSQLQVKKTVELQPTSGSLRP 792

  Fly   762 AHWVVN 767
            ....||
 Frog   793 RSRTVN 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124	55/264 (21%)
		Ion_trans	441..677	CDD:334124	66/274 (24%)
		Ion_trans	769..1050	CDD:334124
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
tpcn1	XP_012825344.2	Ion_trans	144..322	CDD:395416	46/249 (18%)
		Ion_trans	432..683	CDD:395416	66/265 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910