DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cac and lig1

DIOPT Version :9

Sequence 1:	NP_001356945.1	Gene:	cac / 32158	FlyBaseID:	FBgn0263111	Length:	2110	Species:	Drosophila melanogaster
Sequence 2:	XP_002941929.1	Gene:	lig1 / 100271763	XenbaseID:	XB-GENE-1009779	Length:	1040	Species:	Xenopus tropicalis

Alignment Length:	229	Identity:	50/229 - (21%)
Similarity:	83/229 - (36%)	Gaps:	60/229 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   673 AQELTAAEEEQVEEDKEKQLQELEKEMEALQADGVHVENGDGAVAPSKS--KGKKKEE---EKKE 732
            :.::::.::.:.:..:||..:|.||:.:..:.    |:......||.|.  |.:||||   ||..
Frog   296 SDKVSSKDDSEGKSSEEKSDEEPEKKADPAKP----VKQISSFFAPKKPAIKTEKKEEIMNEKNA 356

  Fly   733 EEEVTE-GPKPMLPYSSMF-ILSPT--------NPIRRGAH------WV--VNLPYFDFFIMVVI 779
            .|...| .|||....||.| .:.|.        ||.:...|      |.  ..:||
Frog   357 SETSLEASPKPKKTVSSFFGAIKPEPSEDQAVYNPSKSSYHPINDACWSNGQKVPY--------- 412

  Fly   780 SMSSIALAAE-DPVRENSRRNKILNYFDYAFTGVFTIEMLLKIVDLGVILHPGSYLREFWNIMDA 843
                :|:|.. :.:.|.|.|.|             .||.|...:...:.|.||..|...:..::.
Frog   413 ----LAVARTFERIEEESARLK-------------NIETLSNFLRSVIALTPGDLLPCIYLCLNR 460

  Fly   844 VVVICAAVSFGFDMS------GSSAGQNLSTIKS 871
            :......:..|...:      ..:.|:.|..|||
Frog   461 LGPAYEGLELGIGETILMKAVAQATGRQLEKIKS 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cac	NP_001356945.1	Ion_trans	37..324	CDD:334124
		Ion_trans	441..677	CDD:334124	0/3 (0%)
		Ion_trans	769..1050	CDD:334124	21/110 (19%)
		Ion_trans	1094..1345	CDD:334124
		GPHH	1346..1416	CDD:339854
		Ca_chan_IQ	1418..1492	CDD:337190
lig1	XP_002941929.1	PTZ00121	<157..>369	CDD:173412	21/76 (28%)
lig1	XP_002941929.1	PLN03113	268..1020	CDD:215584	50/229 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900