| Sequence 1: | NP_572771.1 | Gene: | CG10362 / 32157 | FlyBaseID: | FBgn0030358 | Length: | 1037 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_776152.1 | Gene: | PDZD8 / 118987 | HGNCID: | 26974 | Length: | 1154 | Species: | Homo sapiens |
| Alignment Length: | 1191 | Identity: | 289/1191 - (24%) |
|---|---|---|---|
| Similarity: | 483/1191 - (40%) | Gaps: | 263/1191 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 ILLLCLIFLLIGGVVMILLQYLIFIKFSNLPDESEEQKQANA-KYTLP---LNIKQ----TARNL 64
Fly 65 KRLSNSGLGGGAGNGCENHQESLRRASALVSLNFVMQFLFHEFKNSNRVRKWFYRKLSIELDELI 129
Fly 130 SKTTTGKLLDKLTIKELELGDQFPDVKSLS-VHNV------ELDKDEQRI------ENLDLLLDI 181
Fly 182 NYVGNFTTSIDADMVLGKKGSITLRVKQLSGMARLQFTRKPYTHWSISFLGDPELILDIESKYQG 246
Fly 247 RQMQSNITNLISNQIRKAVRRKHTLPNYKLRYKPFFHWTA----EEDASDCDIQ----PNGLLTV 303
Fly 304 KLAELSRLM---GYPGASETYCTITLAPVPFIEASQRDSRNVLISLDVFIHKAKNQQIGIVFK-- 363
Fly 364 QS----GSQVVRIESVLPNTPACKSNLLAGDVLVAIEGRPVTTIQQIAKVVKTLQATVFSLRIER 424
Fly 425 IIPGIIRNDAILED-----------------FE-----------------KYEDIGD-------- 447
Fly 448 -------------LPS---------------------SYPCQPKLETDEAATADPTPKHLVVKPS 478
Fly 479 LSGTPTNSPKKSNLIAKAIKKTMSRESGDKDRDKDKDKDKDKDK--------DKDKDKD-KDKDK 534
Fly 535 DKDK-------GKEEVEEPVNYFYQHSTIDCP------------FSPLIHMEDV---------CS 571
Fly 572 FQLDNSSRFLNVCVFGK---SAGESVLLGYNNVQIGQILVECSETSLNQCLKQISLNPASLQAVK 633
Fly 634 THP----LSNQSGFNPNLCFGDILFGFSWM--GNPNLTVGDVPIKSTSKSQSPARNPLAGDRVAS 692
Fly 693 EDQSQFLKLTSSMADSSTSGESSSGTTAAPRAHDFVRTHFHRATQCDFCGKKIWLKDAMQCQECS 757
Fly 758 MCCHKKCIVKCQMAT-VCGPVDCTGSIPATSSTPSMASRPEFTITQADNPQIVDSST--GATPFD 819
Fly 820 ETSAASGGDQGQIQSPTASGLDVHRSSLTGMLAQGIKRQASNLDIPGIVSSLTGSGQQVNSKSLP 884
Fly 885 PSPQHTPSRKSSIVEEATPALQQNPFESVTQHLEALPLDCPELSFEQVIVITEPIIRHTRNEDLM 949
Fly 950 NLAKSTSKLLYAALPPDERVAKINELLTKLKVALDAETEGYTLMNDAEKATESSPWKS------D 1008
Fly 1009 RSDERVQALSIIMLYLCTGLQ 1029 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG10362 | NP_572771.1 | PDZ | 358..424 | CDD:294084 | 23/71 (32%) |
| DegQ | <370..437 | CDD:223343 | 23/66 (35%) | ||
| C1 | 725..774 | CDD:237996 | 24/49 (49%) | ||
| PDZD8 | NP_776152.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 66..90 | 4/24 (17%) | |
| PDZ_signaling | 364..441 | CDD:238492 | 25/82 (30%) | ||
| Atrophin-1 | <517..>635 | CDD:331285 | 15/117 (13%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 548..612 | 10/63 (16%) | |||
| C1 | 841..883 | CDD:237996 | 21/41 (51%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 955..999 | 11/58 (19%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1132..1154 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165145877 | |
| Domainoid | 1 | 1.000 | 160 | 1.000 | Domainoid score | I4069 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3532 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 299 | 1.000 | Inparanoid score | I2720 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG50075 | |
| OrthoDB | 1 | 1.010 | - | - | D1195477at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0007039 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89910 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_108089 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR21519 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4025 |
| SonicParanoid | 1 | 1.000 | - | - | X5132 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.800 | |||||