Protein Alignment Sclp and LRRC20

DIOPT Version :10

• Sequence 1: NP_001259475.1
• Gene: Sclp / 32156
• FlyBaseID: FBgn0030357
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_997002.1
• Gene: LRRC20 / 55222
• HGNCID: 23421
• Length: 184
• Species: Homo sapiens
• Alignment Length: 158
• Identity: 51/158 - (32%)
• Similarity: 88/158 - (55%)
• Gaps: 8/158 - (5%)

  Fly    76 GQGVIRVVQRCEDAKE--NHKLDLSSCELMQIPDAVYHLMRNT----ELITCNLSGNVLKSVSPK 134
            |:.|.||.::..:..|  :..|||:.|:|:..|..:|.::||.    .|||  |:.|.|||::.|
Human     6 GEAVARVARKVNETVESGSDTLDLAECKLVSFPIGIYKVLRNVSGQIHLIT--LANNELKSLTSK 68

  Fly   135 FSQKFSTITDLNLSHNKLSRLPEEFASLSALTKLNISNNSFIVLPQVVFKLQSLASLDAQNNAIL 199
            |...||.:.:|:|..|.|.|||.|.::|..|..:::|.|.|...|:.:..|.:|.:::.:.|.|:
Human    69 FMTTFSQLRELHLEGNFLHRLPSEVSALQHLKAIDLSRNQFQDFPEQLTALPALETINLEENEIV 133

  Fly   200 EIDTDEAITSDNLALVDLRNNPLSRNCR 227
            ::..::......|..::||.|||:...|
Human   134 DVPVEKLAAMPALRSINLRFNPLNAEVR 161

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sclp	NP_001259475.1	LRR	<93..>223	CDD:443914	44/133 (33%)
		leucine-rich repeat	93..115	CDD:275380	7/21 (33%)
		leucine-rich repeat	116..141	CDD:275380	11/28 (39%)
		leucine-rich repeat	142..164	CDD:275380	9/21 (43%)
		leucine-rich repeat	165..187	CDD:275380	6/21 (29%)
		leucine-rich repeat	188..211	CDD:275380	3/22 (14%)
LRRC20	NP_997002.1	LRR	<26..>156	CDD:443914	43/131 (33%)
		leucine-rich repeat	26..47	CDD:275380	7/20 (35%)
		LRR 1	51..72		10/22 (45%)
		LRR 2	75..96		8/20 (40%)
		leucine-rich repeat	76..98	CDD:275378	9/21 (43%)
		LRR 3	98..120		5/21 (24%)
		leucine-rich repeat	99..121	CDD:275378	6/21 (29%)
		LRR 4	121..141		3/19 (16%)
		leucine-rich repeat	122..145	CDD:275378	3/22 (14%)
		LRR 5	145..167		7/17 (41%)