DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sclp and K08E7.8

DIOPT Version :9

Sequence 1:	NP_001259475.1	Gene:	Sclp / 32156	FlyBaseID:	FBgn0030357	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001040969.1	Gene:	K08E7.8 / 178213	WormBaseID:	WBGene00010675	Length:	176	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	67/170 - (39%)
Similarity:	100/170 - (58%)	Gaps:	5/170 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 AGQGVIRVVQRCEDAKENHKLDLSSCELMQIPDAVYHLMRNTELITCNLSGNVLKSVSPKFSQKF 139
            ||:||.:||:|||.|||:..||||||:||.:.||||.|::..|:...::..|..|....||..||
Worm     7 AGKGVTQVVERCEAAKESGFLDLSSCQLMYMADAVYMLIKGYEITKVSIQDNGFKKFPKKFVIKF 71

  Fly   140 STITDLNLSHNKLSRLPEEFASLSALTKLNISNNSFIVLPQVVFKLQSLASLDAQNNAILEIDTD 204
            .|.|.||:::|::|.:|||.|:.::|..||.:.|.....|:...:|::|..||...|.:.|||.|
Worm    72 PTATILNMANNEISEIPEEVATWTSLKGLNAAKNKISKFPEPFLQLKNLIYLDLNGNQLEEIDVD 136

  Fly   205 EAITSDNLALVDLR---NNPLSRNCRRKLQSFKTPFHLEI 241
             ...|...||:.|.   |..|....::||::.| |..|::
Worm   137 -LFYSSLPALIKLNLSGNEGLGDETKKKLKALK-PEKLDL 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sclp	NP_001259475.1	LRR_RI	77..>232	CDD:238064	62/157 (39%)
		LRR_8	93..152	CDD:290566	25/58 (43%)
		leucine-rich repeat	93..115	CDD:275380	13/21 (62%)
		leucine-rich repeat	116..141	CDD:275380	7/24 (29%)
		LRR_8	140..198	CDD:290566	20/57 (35%)
		leucine-rich repeat	142..164	CDD:275380	9/21 (43%)
		leucine-rich repeat	165..187	CDD:275380	6/21 (29%)
		leucine-rich repeat	188..211	CDD:275380	9/22 (41%)
K08E7.8	NP_001040969.1	leucine-rich repeat	50..73	CDD:275378	6/22 (27%)
		leucine-rich repeat	74..96	CDD:275378	9/21 (43%)
		LRR_RI	<76..174	CDD:238064	33/99 (33%)
		LRR_8	95..153	CDD:290566	18/58 (31%)
		leucine-rich repeat	97..119	CDD:275378	6/21 (29%)
		leucine-rich repeat	120..144	CDD:275378	9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167317
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44023
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1291630at2759
OrthoFinder	1	1.000	-	-		FOG0007270
OrthoInspector	1	1.000	-	-		oto18111
orthoMCL	1	0.900	-	-		OOG6_108515
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3858
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.780