Protein Alignment Upf1 and AT1G16800

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_001322185.1
• Gene: AT1G16800 / 838251
• AraportID: AT1G16800
• Length: 2226
• Species: Arabidopsis thaliana
• Alignment Length: 1228
• Identity: 276/1228 - (22%)
• Similarity: 434/1228 - (35%)
• Gaps: 431/1228 - (35%)

  Fly     7 APSSALS----FLDMDD----------NELLPGAD----TQPT------QYDYRDFTMPSTSQSQ 47
            |.|||:.    .|..||          :.|:|.|:    .:|.      |.:..|.|:..|.:..
plant   894 ACSSAVQAIRHVLSSDDVDIEQLAEQISRLVPKANEYQILKPVDVVGKLQDNMMDLTVDETEKES 958

  Fly    48 TQNDQLEIAQRCSAGDSHPRLASITN-----------------DLADLQFEEEDDEPGSS-YVKE 94
            .:|  |....:....|.:..|..|.|                 .|:.|...|.|....|| .|::
plant   959 LKN--LPSLHKSHQPDINKTLLPIKNISQISSLKKSTSSIDASKLSALVLSERDVTVSSSNIVRD 1021

  Fly    95 LPP-------------HACKYCGIHDPATVVMCNNCRKWF--CNGRGSTSGSH------------ 132
            ||.             .|.|...:.||.:..:..|.:|..  ...||::..:.
plant  1022 LPTTNAEPSKAAGMSREAEKRQNVEDPVSSGIRPNLKKATDELGPRGTSKEAQKSAISNAKGMDL 1086

  Fly   133 --IINH---------LVRAKHREVTLHGEGPLGETILECYSCGVRNVFVLGFIPAKADSVVVLLC 186
              ::|.         |...|.:.:.|...||:                    :|.:.   |:.||
plant  1087 RKVVNETEVDPLDLALKSLKRQSLPLAKSGPI--------------------VPKRQ---VIQLC 1128

  Fly   187 RQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRARQISAAQINKLEELWKENIE 251
                      ..:|...::|               |..|.|..|.|.      .|||:.:::.::
plant  1129 ----------APVNKKSDRW---------------QRQEAGFKRFRP------PKLEDWFRKILQ 1162

  Fly   252 ATFQDLEKPGIDSEP----------AHVLLRYEDGYQYEKTFGPLV--RLEAEYDQKLKESATQE 304
            ..:..:  .|:.|..          ..|.:|:....||.:.|.|||  ..:|:.....:|.::.|
plant  1163 MDYYAI--VGLASTKKDESQNVGKFREVPVRFGSPEQYIQIFQPLVLEEFKAQLQSSFQEISSLE 1225

  Fly   305 NIE-----------------VRW----DVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELY 348
            .|.                 ||:    :.|.|.|:.       :::|:.|...:......||
plant  1226 EIYYGVISVLSIERVDDFHFVRFMQDENDGSNSKSF-------SENDLVLFTKEHPENSNVG--- 1280

  Fly   349 NPWSEIGHVIKVPDNFGDD--------VGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALC 405
                 :..:.||.....||        |.|.|:::::...:...|......|..:....:|..:.
plant  1281 -----VNMMGKVEGREWDDKKRTSILNVRLYLQNASSRLNQARRNLLERSQWHASRILNITSQIR 1340

  Fly   406 KF----AIDRNSVSNFIYSRLLGHGRADSN--DEVLFRGPQPKLFSAPH------LPDLNRSQVY 458
            :|    .|....|...|.|.:     .|||  .||    .:..|.|.||      ....|.||:.
plant  1341 EFQALSCIKDIPVLPLILSPM-----NDSNYDSEV----KRSDLRSLPHSLQQILKSSFNESQLQ 1396

  Fly   459 AVKHALQR-------PLSLIQGPPGTGKTVTSATIVYQLV------------------------- 491
            |:..|:..       .:||||||||||||.|...|:..|:
plant  1397 AISVAIGSSNLMKAFDISLIQGPPGTGKTRTIVAIISGLLASASHKTSDRGNSEPGHSSSTSRQG 1461

  Fly   492 --------------------------------KLHGGTVLVCAPSNTAVDQLTEKIHRTNL---- 520
                                            |...|.||:||.||.|||:|..:|....:
plant  1462 MNPSVAVARAWQDAALAKQLNDNSETNRKIAEKNGRGRVLICAQSNAAVDELVSRISSLGIYGRD 1526

  Fly   521 ------KVVRVC-------------------------------AKSREAIDSPVSFLALHNQIRN 548
                  .:|||.                               :||.:..||.....:...::.:
plant  1527 GKMFKPYLVRVGNAKTVHSNSMPFFLDTLVDQRLAEERMRINESKSNKGADSSALLRSNLEKVVD 1591

  Fly   549 METNSELKKL----------------QQLKDETGELSS--------------------------A 571
            ..|:.|.|:.                ...||:.|:|.|                          |
plant  1592 QITHFEAKRANINQESLDAKDKPENEHHNKDDDGKLMSDAELGIRLRRLYEQKRKIYKDLSAVQA 1656

  Fly   572 DEKR----YRNLKRAAENQLLEAADVICCTCVGAGDGRLSRV-----------------KFTSIL 615
            .|::    .|.||:.....:|:.|.::..|..|.| |.|..|                 .|.:::
plant  1657 QERKANYEMRTLKQKLRKSILKEAQIVVTTLSGCG-GDLYSVCAESLAAHKFGSPSEDNLFDAVV 1720

  Fly   616 IDESMQSTEPECMVPVVL----GAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERLVVLGIRP 676
            |||:.|:.||..::|:.|    |.| .|:|||..||...|:...|::.....|:||||...|...
plant  1721 IDEAAQALEPATLIPLQLLKSRGTK-CIMVGDPKQLPATVLSNVASKFLYECSMFERLQRAGYPI 1784

  Fly   677 FRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPER--P-MFFLVTQGQEEIA 738
            ..|..|||||||:.:|||..||:..|.|||....:    ..|:.:...  | :|:.:..|||..:
plant  1785 LMLTQQYRMHPEICRFPSMHFYDNKLLNGVDMSSK----SAPFHENHHLGPYVFYDIVDGQEHRS 1845

  Fly   739 GSGTSFLNRTEA-ANVEKITTRFLKAGIKPE----QIGIITPYEGQRAYLVQYMQYQGSLHSRLY 798
            |..:|..|..|| |.|:.:  ||.|.....|    :|||||||:.|.|.|  ..::.|:..:::.
plant  1846 GDSSSVCNEQEAEAAVQLL--RFFKKRYPSEFVAGRIGIITPYKRQLAVL--RSRFTGAFGAQVT 1906

  Fly   799 QEIEIASVDAFQGREKDIIIMSCVRSN-------ERQGIGFLNDPRRLNVALTRAKFGIIIVGNP 856
            .::|:.:||.|||:|.||:::|.||:.       .:..|||:.|.||:||||||||..:.::||.
plant  1907 ADMEMNTVDGFQGKEVDILVLSTVRATHSAPDGVNQSRIGFVADVRRMNVALTRAKLSLWVLGNT 1971

  Fly   857 KVLAKQQLWNHLLNFYKDRKVLV----------------EGSLNNLKESLIHFQKPKK 898
            :.|.:...|..|:...|:|:|::                :....||.:   :|.||.|
plant  1972 RTLQRDHNWGALVKDAKEREVIIPVKRPYNYMFGENVMEQNHSENLPK---NFPKPDK 2026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391	28/175 (16%)
		1B_UPF1-like	302..390	CDD:394815	19/116 (16%)
		TIGR00376	355..880	CDD:273041	189/747 (25%)
		DEXXQc_UPF1	451..684	CDD:350797	88/404 (22%)
AT1G16800	NP_001322185.1	DEXXQc_SETX	1390..1792	CDD:438712	88/403 (22%)
		AAA_12	1769..1972	CDD:463780	79/210 (38%)