Protein Alignment Upf1 and LBA1

DIOPT Version :9

• Sequence 1: NP_001285145.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_199512.2
• Gene: LBA1 / 834747
• AraportID: AT5G47010
• Length: 1254
• Species: Arabidopsis thaliana
• Alignment Length: 1210
• Identity: 627/1210 - (51%)
• Similarity: 765/1210 - (63%)
• Gaps: 170/1210 - (14%)

  Fly     4 DTYAPS-SALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQSQTQNDQLEIA------QRCSA 61
            ||.|.. :.|.|....|:|           :||:||..|:.  ..|.:|.:.||      :..:|
plant    16 DTVADEYTFLEFNTQGDSE-----------FDYQDFGSPTA--WPTPSDSISIADVADRGEGGAA 67

  Fly    62 GDSHPRLAS---------------------------------ITNDLADLQFEEEDDEPGSSYVK 93
            .|.|...:|                                 :...:.:|.|||..|:.|..|.|
plant    68 ADHHSEASSPSSLSAGAGNGAKVGRGGVGGSGGVSSSSQVDALAAGVGNLNFEETGDDDGFDYGK 132

  Fly    94 -ELPPHACKYCGIHDPATVVMCN--NCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGE 155
             :...||||||||.:||.||.||  :|||||||.||:||||||:||||||||:||.||.:.||||
plant   133 NDFTEHACKYCGISNPACVVRCNVASCRKWFCNSRGNTSGSHIVNHLVRAKHKEVCLHRDSPLGE 197

  Fly   156 TILECYSCGVRNVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLV 220
            ||||||:||.||||:||||.||.|||||||||.||...|:|||||||..||.|||.|||||.|||
plant   198 TILECYNCGCRNVFLLGFISAKTDSVVVLLCRDPCLNVNALKDMNWDLSQWCPLIDDRCFLPWLV 262

  Fly   221 KQPSEQGQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGP 285
            |.||||.|||||||||.||||:|||||.|.:||.:||||||:|.||..|..:|||.|||:..|.|
plant   263 KVPSEQEQLRARQISAQQINKIEELWKTNPDATLEDLEKPGVDDEPQPVQPKYEDAYQYQNVFAP 327

  Fly   286 LVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMKLMHGDELRLHYVGELYNP 350
            |::|||:||:.:|||.::||:.||||:|||||.:|||...|.:::::|:.||||||.|.|:..:|
plant   328 LIKLEADYDKMMKESQSKENLTVRWDIGLNKKRVAYFVFPKEENELRLVPGDELRLRYSGDAVHP 392

  Fly   351 -WSEIGHVIKVPDNFGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKFAIDRNSV 414
             |..:|||||:...  ::|.|||:::...|:.....|:|||:||.||||||..|:..||:|..||
plant   393 SWQSVGHVIKLTAQ--EEVALELRANQGVPIDVNHGFSVDFVWKSTSFDRMQGAMKNFAVDETSV 455

  Fly   415 SNFIYSRLLGHGRADSNDEV---LFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPG 476
            |.:||.:||||       ||   :.|...|:.|..|.||:||.|||.|||..||:|:||||||||
plant   456 SGYIYHQLLGH-------EVEAQMVRNTLPRRFGVPGLPELNASQVNAVKSVLQKPISLIQGPPG 513

  Fly   477 TGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLA 541
            ||||||||.|||.:.|...|.||||||||.|||||.|||..|.|||||:|||||||:.|||.:|.
plant   514 TGKTVTSAAIVYHMAKQGQGQVLVCAPSNVAVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLT 578

  Fly   542 LHNQIRNMETN--SELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDG 604
            ||.|:|:::|:  |||.||||||||.|||||:|||:|:|||||.|.::.::|||||||||||.|.
plant   579 LHYQVRHLDTSEKSELHKLQQLKDEQGELSSSDEKKYKNLKRATEREITQSADVICCTCVGAADL 643

  Fly   605 RLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFERL 669
            |||..:|..:|||||.|:|||||::|:|||.||::|||||||||||:||||||||||:|||||||
plant   644 RLSNFRFRQVLIDESTQATEPECLIPLVLGVKQVVLVGDHCQLGPVIMCKKAARAGLAQSLFERL 708

  Fly   670 VVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLK-LDFPWPQPERPMFFLVTQG 733
            |.|||:|.||:|||||||.||:||||.||||:|||||...:|:.. :|||||.|.|||||.|..|
plant   709 VTLGIKPIRLQVQYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLG 773

  Fly   734 QEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRLY 798
            ||||:.||||:|||||||||||:.|.|||:|:.|.|||:||||||||||:|.||...|||..:||
plant   774 QEEISASGTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLY 838

  Fly   799 QEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQ 863
            :|||:||||:|||||||.||:|||||||.|||||||||||||||||||::||:|:||||||:||.
plant   839 KEIEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQP 903

  Fly   864 LWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSIYD 928
            |||.||..||:.:.||||.|||||:|::.||||:|:.|...:
plant   904 LWNGLLTHYKEHECLVEGPLNNLKQSMVQFQKPRKIYNDRRL----------------------- 945

  Fly   929 RSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNFGG 993
                               .||| |.|..||...|.|.|:::.       .|..|.|||:....|
plant   946 -------------------FYGG-GAGMIGNDNFGSGNPNADR-------RGSRGRAGGSYLPSG 983

  Fly   994 AGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRAIQ 1058
            . |:.|...||  ..||             |:|..........||    ....||.......|:
plant   984 P-PNGARPGLH--PAGY-------------PIPRVPLSPFPGGPP----SQPYAIPTRGPVGAV- 1027

  Fly  1059 QQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYSQH 1123
                   |....||..|.|.||..:.||:....:..:..|   ||.|..|.
plant  1028 -------PHAPQPGNHGFGAGRGTSVGGHLPHQQATQHNV---GTIGPSLN-------------- 1068

  Fly  1124 PMPLSLQMTQPS-GFALSQQPELSQDFGQISQMDGLLSQD 1162
             .||....:||| |..|||....||.|.....|.| :|||
plant  1069 -FPLDSPNSQPSPGGPLSQPGYGSQAFRDGFSMGG-ISQD 1106

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_001285145.1	UPF1_Zn_bind	98..249	CDD:286500	118/152 (78%)
		DNA2	122..897	CDD:224037	517/781 (66%)
		Mis12	210..299	CDD:283509	59/88 (67%)
		AAA_19	458..>515	CDD:289986	41/56 (73%)
		AAA_12	661..857	CDD:289832	144/196 (73%)
LBA1	NP_199512.2	DNA2	164..929	CDD:224037	513/773 (66%)
		DEXXQc_UPF1	488..723	CDD:350797	166/234 (71%)
		Med15	<983..>1202	CDD:312941	45/171 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	298	1.000	Domainoid score	I340
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2185
Inparanoid	1	1.050	1115	1.000	Inparanoid score	I27
OMA	1	1.010	-	-		QHG54950
OrthoDB	1	1.010	-	-		D62494at2759
OrthoFinder	1	1.000	-	-		FOG0000219
OrthoInspector	1	1.000	-	-		oto3801
orthoMCL	1	0.900	-	-		OOG6_101981
Panther	1	1.100	-	-	LDO	PTHR10887
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3712
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840