Protein Alignment Upf1 and AT5G35970

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: NP_198446.3
• Gene: AT5G35970 / 833589
• AraportID: AT5G35970
• Length: 961
• Species: Arabidopsis thaliana
• Alignment Length: 951
• Identity: 246/951 - (25%)
• Similarity: 387/951 - (40%)
• Gaps: 226/951 - (23%)

  Fly    67 RLASITNDLADLQFEEEDDEPGSSYV---------KELPPHACKYCGIHDP-ATVVMCNNCRKWF 121
            |.:::::.|...:.|:.:|...|..:         |||...|....|  || ....:..|..||
plant    65 RKSNVSDKLRFKKIEKRNDNTESESLSVVEEPKNDKELSLRALNQNG--DPLGRRDLGRNVVKW- 126

  Fly   122 CNGRGSTSGSHIINHLVRAKHRE-VTLHGEGPLGETILECYSCGVRNVF----VLGFIPAKADSV 181
                        |:..::|...: .|...:|...| :.:....|:..|.    .|..||....|.
plant   127 ------------ISQAMKAMASDFATAEVQGEFSE-LRQNVGSGLTFVIQAQPYLNAIPMPLGSE 178

  Fly   182 VVLLCRQPCA--------AQNSLKDM-----------NW-DQEQWKPLIADRCFLAWLVKQPSEQ 226
            |:  |.:.|.        .|..|:|:           :| :.|.||           |:|:.:..
plant   179 VI--CLKACTHYPTLFDHFQRELRDVLQDLERKNIMESWKESESWK-----------LLKEIANS 230

  Fly   227 GQLRARQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEA 291
            .|.|.....|||...::.:.              |:|||....:....|  ::......|  |:.
plant   231 AQHREVARKAAQAKPVQGVL--------------GMDSEKVKAIQERID--EFTSQMSQL--LQV 277

  Fly   292 EYDQKLKESATQENIEV--RWDVGLNKKTIAYFTLAKTDSDMKL---------------MHGDEL 339
            |.|.:|:  .|||.::|  ..|...:......|.:...|:..:|               :.|..|
plant   278 ERDTELE--VTQEELDVVPTPDESSDSSKPIEFLVRHGDAPQELCDTICNLYAVSTSTGLGGMHL 340

  Fly   340 RLHYVG-------ELYNPWSEIGHVIKVPD---------------NFGDD---VGLELKSSTNAP 379
            .|..||       ...:|...:  .|:|.|               |.|:|   :|:.|:|....|
plant   341 VLFKVGGNHRLPPTTLSPGDMV--CIRVCDSRGAGATACTQGFVHNLGEDGCSIGVALESRHGDP 403

  Fly   380 V------KCTSNFTVDFIWKCTSFDRMTRALC---KFAIDRNSVSNFIYSRLLGHGR----ADSN 431
            .      |......:..:....:::|...||.   |..:.:.:.|..:.:.|.|.|.    .:.|
plant   404 TFSKLFGKSVRIDRIHGLADALTYERNCEALMLLQKNGLQKKNPSISVVATLFGDGEDITWLEQN 468

  Fly   432 DEV------LFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQL 490
            |.|      |...|..|||      |.::.:..|:....:||:.::|||||||||.....::...
plant   469 DYVDWSEAELSDEPVSKLF------DSSQRRAIALGVNKKRPVMIVQGPPGTGKTGMLKEVITLA 527

  Fly   491 VKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLAL----HNQIRNMET 551
            |: .|..|||.||:|.|||.:.||:....|.:|||...:|  |.|.|:..:|    ::::.:...
plant   528 VQ-QGERVLVTAPTNAAVDNMVEKLLHLGLNIVRVGNPAR--ISSAVASKSLGEIVNSKLASFRA 589

  Fly   552 NSELKK-------------------LQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCT 597
            ..|.||                   ::||..:.|:.....||.       ...::|..|.|:..|
plant   590 ELERKKSDLRKDLRQCLRDDVLAAGIRQLLKQLGKTLKKKEKE-------TVKEILSNAQVVFAT 647

  Fly   598 CVGAGDGRLSRVK-FTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGL 661
            .:||.|..:.|:: |..::|||:.||.||.|.:|::.| |:.||.||.|||.|||:.:||...||
plant   648 NIGAADPLIRRLETFDLVVIDEAGQSIEPSCWIPILQG-KRCILSGDPCQLAPVVLSRKALEGGL 711

  Fly   662 SQSLFERLVVL--GIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQ--- 721
            ..||.||...|  |:...:|..||||:..::.:.|...|.|.|::...... .|.:|.|:.:
plant   712 GVSLLERAASLHDGVLATKLTTQYRMNDVIAGWASKEMYGGWLKSAPSVAS-HLLIDSPFVKATW 775

  Fly   722 -PERPMFFLVTQ--------GQEE---IAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIIT 774
             .:.|:..|.|:        |.||   .||:| |..|..||..|.......:.||:.|..|.:.:
plant   776 ITQCPLVLLDTRMPYGSLSVGCEERLDPAGTG-SLYNEGEADIVVNHVISLIYAGVSPMAIAVQS 839

  Fly   775 PYEGQRAYLVQYMQYQGSLHSRL-----YQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLN 834
            ||..|    ||.      |..||     ...:|:|::|:|||||.|.:|:|.||||....:|||.
plant   840 PYVAQ----VQL------LRERLDDFPVADGVEVATIDSFQGREADAVIISMVRSNNLGAVGFLG 894

  Fly   835 DPRRLNVALTRAKFGIIIVGNPKVLAKQ----QLWNHLLNF 871
            |.||:|||:|||:..:.:|.:...:...    :|..|:..|
plant   895 DSRRMNVAITRARKHVAVVCDSSTICHNTFLARLLRHIRYF 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391	35/176 (20%)
		1B_UPF1-like	302..390	CDD:394815	25/135 (19%)
		TIGR00376	355..880	CDD:273041	179/604 (30%)
		DEXXQc_UPF1	451..684	CDD:350797	85/258 (33%)
AT5G35970	NP_198446.3	TIGR00376	277..942	CDD:273041	196/692 (28%)