DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Upf1 and Ct55

DIOPT Version :9

Sequence 1:	NP_001285145.1	Gene:	Upf1 / 32153	FlyBaseID:	FBgn0030354	Length:	1180	Species:	Drosophila melanogaster
Sequence 2:	NP_083418.1	Gene:	Ct55 / 75013	MGIID:	1922263	Length:	236	Species:	Mus musculus

Alignment Length:	208	Identity:	38/208 - (18%)
Similarity:	59/208 - (28%)	Gaps:	103/208 - (49%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 MPSTSQSQT---------QNDQLEIAQRCSAGDSHPR--LASITN-------------------- 73
            :|:..:.|:         .||..|     ...:||.|  |||||:
Mouse    75 LPAAVEEQSPRGLNAVTVDNDHDE-----EPSESHMRILLASITSLVGDADYNGHGFSFSLDIAC 134

  Fly    74 --------DLADLQFEEEDDEPGSSYVKELPPHACKYCGIHDPATVVMCNNCRKWFCNGRGSTSG 130
                    ||.:::|.:|.|......:...|   .|:|.:::....               .|.|
Mouse   135 KDFKPYNGDLVEIEFSDEQDTQSRRAILVKP---LKHCHLNEVRVT---------------RTDG 181

  Fly   131 SHIINHLVRAKHREVTLHGEGPLGETILECYSCGVRNVFVL-------GFIPAKADSVVVLLCRQ 188
            |                  .|.|.:||.          |.|       |::|...|.|.|:
Mouse   182 S------------------TGVLEDTIF----------FTLDSLKLPSGYVPQPDDVVNVV---- 214

  Fly   189 PCAAQNSLKDMNW 201
              |.|:...:..|
Mouse   215 --AVQSMQSNYFW 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_001285145.1	UPF1_Zn_bind	98..249	CDD:286500	19/111 (17%)
		DNA2	122..897	CDD:224037	17/87 (20%)
		Mis12	210..299	CDD:283509
		AAA_19	458..>515	CDD:289986
		AAA_12	661..857	CDD:289832
Ct55	NP_083418.1	S1-like	176..228	CDD:291136	17/99 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900