| Sequence 1: | NP_001285145.1 | Gene: | Upf1 / 32153 | FlyBaseID: | FBgn0030354 | Length: | 1180 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_016882594.1 | Gene: | UPF1 / 5976 | HGNCID: | 9962 | Length: | 1137 | Species: | Homo sapiens |
| Alignment Length: | 1230 | Identity: | 743/1230 - (60%) |
|---|---|---|---|
| Similarity: | 864/1230 - (70%) | Gaps: | 163/1230 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MSVDTYAPSS-ALSFLDMDDNELLPGADTQPTQYDYRDFTMPSTSQSQ----------------- 47
Fly 48 ----TQNDQLE-------IAQRCSAGDSHPRLASITNDLADLQFEEEDDEPGSSYVKELPPHACK 101
Fly 102 YCGIHDPATVVMCNNCRKWFCNGRGSTSGSHIINHLVRAKHREVTLHGEGPLGETILECYSCGVR 166
Fly 167 NVFVLGFIPAKADSVVVLLCRQPCAAQNSLKDMNWDQEQWKPLIADRCFLAWLVKQPSEQGQLRA 231
Fly 232 RQISAAQINKLEELWKENIEATFQDLEKPGIDSEPAHVLLRYEDGYQYEKTFGPLVRLEAEYDQK 296
Fly 297 LKESATQENIEVRWDVGLNKKTIAYFTLAKTDS-----------DMKLMHGDELRLHYVGELYNP 350
Fly 351 WSEIGHVIKVPDN--------FGDDVGLELKSSTNAPVKCTSNFTVDFIWKCTSFDRMTRALCKF 407
Fly 408 AIDRNSVSNFIYSRLLGHGRADSNDEVLFRGPQPKLFSAPHLPDLNRSQVYAVKHALQRPLSLIQ 472
Fly 473 GPPGTGKTVTSATIVYQLVKLHGGTVLVCAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPV 537
Fly 538 SFLALHNQIRNMETNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAG 602
Fly 603 DGRLSRVKFTSILIDESMQSTEPECMVPVVLGAKQLILVGDHCQLGPVVMCKKAARAGLSQSLFE 667
Fly 668 RLVVLGIRPFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLK-LDFPWPQPERPMFFLVT 731
Fly 732 QGQEEIAGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSR 796
Fly 797 LYQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAK 861
Fly 862 QQLWNHLLNFYKDRKVLVEGSLNNLKESLIHFQKPKKLVNSMNIGAHFMSTIIADAKEVMVPGSI 926
Fly 927 YDRSGGYGQGRQMVGQSMNGGQYGGSGGGPYGNSPLGYGTPSSNSMVGFGLGNGGNGAAGGNNNF 991
Fly 992 GGAGPSWAAAHLHHDSIGYISNEHGAAALGNMPVPVGMFMNMSNIPPRFYNQHQQAIMAVKQNRA 1056
Fly 1057 IQQQTGNFSPGNSGPGVTGVGVGRSATPGGNKKTNKLGKSRVTGGGTGGAPLTQGSSVCNAAPYS 1121
Fly 1122 QHPMPLS-LQMTQPSGFALSQ----QPELSQD--FGQ--ISQMDGLLSQDVAFNASGERS 1172 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Upf1 | NP_001285145.1 | UPF1_Zn_bind | 98..249 | CDD:286500 | 122/150 (81%) |
| DNA2 | 122..897 | CDD:224037 | 599/794 (75%) | ||
| Mis12 | 210..299 | CDD:283509 | 68/88 (77%) | ||
| AAA_19 | 458..>515 | CDD:289986 | 46/56 (82%) | ||
| AAA_12 | 661..857 | CDD:289832 | 162/196 (83%) | ||
| UPF1 | XP_016882594.1 | DNA2 | 145..928 | CDD:224037 | 594/786 (76%) |
| DEXXQc_UPF1 | 489..722 | CDD:350797 | 196/232 (84%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165154056 | |
| Domainoid | 1 | 1.000 | 332 | 1.000 | Domainoid score | I1140 |
| eggNOG | 1 | 0.900 | - | - | E1_COG1112 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2185 | |
| Inparanoid | 1 | 1.050 | 1355 | 1.000 | Inparanoid score | I137 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54950 | |
| OrthoDB | 1 | 1.010 | - | - | D62494at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000219 | |
| OrthoInspector | 1 | 1.000 | - | - | oto91178 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101981 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10887 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1079 |
| SonicParanoid | 1 | 1.000 | - | - | X3712 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 15.800 | |||||