Protein Alignment Upf1 and mov10a

DIOPT Version :10

• Sequence 1: NP_572767.1
• Gene: Upf1 / 32153
• FlyBaseID: FBgn0030354
• Length: 1180
• Species: Drosophila melanogaster
• Sequence 2: XP_002662576.2
• Gene: mov10a / 566858
• ZFINID: ZDB-GENE-091230-8
• Length: 1001
• Species: Danio rerio
• Alignment Length: 709
• Identity: 199/709 - (28%)
• Similarity: 292/709 - (41%)
• Gaps: 170/709 - (23%)

  Fly   277 YQYEKTFGPLVRLEAEYDQKLKESATQENIEVRWDVGLNKKTIAYFTLAKTDSDMK--------L 333
            |:|......|.:.:.|..:.|..|..|....||             .|..|...||        |
Zfish   314 YRYPAYLKELAKYKLEDSEHLPASLKQHLPRVR-------------RLLDTQLCMKNYSERFHLL 365

  Fly   334 MHGDELRLH-----YVGELYNPWSEIGH------VIKVP---DN-----FGDDVGLELKSSTNAP 379
            :|.:|:::.     |  :||.....:..      ::|||   :|     .||.:.:.|....|.|
Zfish   366 LHLEEIQMEVDIKKY--DLYGKTMTLDKTNKKLLILKVPGVAENRPSVLRGDKLNVCLSDDRNQP 428

  Fly   380 VKCTSNFT--VDFIWKCTSFDRMTRALCKFAIDRNSVSNFIYSRL---LGHGRAD-----SNDEV 434
            :.....:.  |:.......|.|  :.|.||..:......|..:|.   |.|...:     :...|
Zfish   429 ITVYEGYVHRVELDKVILGFSR--KLLQKFVNNMKFDVEFNINRFPLRLQHRAVELAVQHALGNV 491

  Fly   435 LFRGPQPKLFSAPHLPDL---------NRSQVYAVKHAL---QRPLS-LIQGPPGTGKTVTSATI 486
            ||  |..|......||.|         |..|..||:|.|   .||.. ||.||||||||||....
Zfish   492 LF--PSDKDTGHSELPHLSMFNKDLENNPEQKAAVQHILSGSSRPAPYLIFGPPGTGKTVTVVEA 554

  Fly   487 VYQLVKLHGGT-VLVCAPSNTAVDQLTEKI--HRTNLKVVRVCAKSREAIDSPVSFLALHNQIRN 548
            :.|:.|....: :|.|||||:|.|.|.|::  |....::.|:||.||:....|...|
Zfish   555 IKQVDKSKAQSHILACAPSNSACDLLCERLLGHVDAHRIYRLCAPSRDPRTVPQKLL-------- 611

  Fly   549 METNSELKKLQQLKDETGELSSADEKRYRNLKRAAENQLLEAAD------VICCTCVGAG---DG 604
                                      ::.|...|.::.||.:.:      :|..|.|.||   .|
Zfish   612 --------------------------KHSNWNEAQDSFLLPSKETLIGYSIIVVTLVTAGRLVSG 650

  Fly   605 RLSRVKFTSILIDESMQSTEPECMVPV------VLGAKQLILVGDHCQLGPVVMCKKAARAGLSQ 663
            .::...||.|.|||:.|:.||||::.:      :.|  ||:|.||..|||||:....|...||.|
Zfish   651 GVAMGHFTHIFIDEAGQAVEPECIIGIAGLLDPLKG--QLVLAGDPQQLGPVLRSPLAQLHGLGQ 713

  Fly   664 SLFERLVVLGIR---------------PFRLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRL 713
            ||.|||:.....               ..:|...||.||.:.:.|:..|||..||  |.|.....
Zfish   714 SLLERLMKRNALYQKSQDDNSKYDSRFVTKLLRNYRSHPAILKIPNELFYENELQ--VFANQMER 776

  Fly   714 KLDFPW---PQPERPMFFLVTQGQEEIAGSGTSFLNRTEAANVEKITTRFL----KAGIK---PE 768
            :....|   |:...|:.|....|::|...:..||.|.||...:.......:    |.|:.   |.
Zfish   777 EAFCQWEHLPRKGFPVVFHGVMGKDEREANSPSFFNVTEIEVIVNYLNNLMQTQGKKGLPKLGPN 841

  Fly   769 QIGIITPYEGQRAYLVQYMQYQGSLHSRLYQEIEIASVDAFQGREKDIIIMSCVRS-------NE 826
            .||||.||..|...:.:.:...|.|  :.:::|::.||:.|||:|:.:||:|.|||       ::
Zfish   842 DIGIIAPYRKQVEKIRKALNTVGEL--KKWKDIKVGSVEEFQGQERKVIIVSTVRSSVNYVKMDQ 904

  Fly   827 RQGIGFLNDPRRLNVALTRAKFGIIIVGNPKVLAKQQLWNHLLNF-----------YKD 874
            ...||||::.:|.|||:||||..:|:||||.:|:|...|...:.:           |||
Zfish   905 DFNIGFLSNEKRFNVAMTRAKGLLIVVGNPVILSKDPTWQKFIQYCEQEQGYTGFDYKD 963

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Upf1	NP_572767.1	UPF1_Zn_bind	98..249	CDD:401391
		1B_UPF1-like	302..390	CDD:394815	23/116 (20%)
		TIGR00376	355..880	CDD:273041	180/618 (29%)
		DEXXQc_UPF1	451..684	CDD:350797	83/278 (30%)
mov10a	XP_002662576.2	DEXXQc_Helz-like	517..749	CDD:350796	82/267 (31%)
		SF1_C_Upf1	750..951	CDD:350195	66/204 (32%)